Curation Details
Interaction ID: IM-28561-1173

Unique identifier for interactor Auniprotkb:Q9NR46
Unique identifier for interactor Buniprotkb:P51114
Alternative identifier for interactor Aintact:EBI-749607
uniprotkb:A8MPS4
uniprotkb:Q8WY61
uniprotkb:Q96JH9
uniprotkb:A6NC47
ensembl:ENSP00000361640.1
ensembl:ENSP00000361645.3
Alternative identifier for interactor Bintact:EBI-713291
uniprotkb:A8K9B8
uniprotkb:Q7Z450
uniprotkb:Q8N6R8
ensembl:ENSP00000350170.3
Aliases for Apsi-mi:shlb2_human(display_long)
uniprotkb:SH3 domain-containing GRB2-like protein B2(gene name synonym)
uniprotkb:SH3GLB2(gene name)
psi-mi:SH3GLB2(display_short)
uniprotkb:KIAA1848(gene name synonym)
uniprotkb:PP578(orf name)
Aliases for Bpsi-mi:fxr1_human(display_long)
uniprotkb:FXR1(gene name)
psi-mi:FXR1(display_short)
uniprotkb:FMR1 autosomal homolog 1(gene name synonym)
uniprotkb:hFXR1p(gene name synonym)
Interaction detection methodspsi-mi:"MI:0398"(two hybrid pooling approach)
First authorSakai et al. (2011)
Identifier of the publicationdoi:10.1126/scitranslmed.3002166
pubmed:21653829
imex:IM-28561
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26511252
imex:IM-28561-1173
Confidence scoreintact-miscore:0.37
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST2
comment:"\"Library for Y2H screening used: human brain\""
curation depth:imex curation
full coverage:Only protein-protein interactions
dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn
dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\""
NCBI Taxonomy identifier for the host organismtaxid:4932(yeasx)
taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
Parameters of the interaction-
Creation date2020/10/05
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bsufficient binding region:215-363
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification