| Unique identifier for interactor A | uniprotkb:P05067 |
| Unique identifier for interactor B | uniprotkb:Q9BYB0 |
| Alternative identifier for interactor A | intact:EBI-77613 uniprotkb:P09000 uniprotkb:P78438 uniprotkb:Q13764 uniprotkb:Q13778 uniprotkb:Q13793 intact:EBI-28985182 uniprotkb:Q6GSC0 uniprotkb:Q8WZ99 uniprotkb:Q9UC33 uniprotkb:Q9UCC8 uniprotkb:Q9UCD1 uniprotkb:Q9UQ58 uniprotkb:Q16011 uniprotkb:Q16014 uniprotkb:Q16019 uniprotkb:Q16020 uniprotkb:Q9BT38 uniprotkb:Q9UCA9 uniprotkb:Q9UCB6 uniprotkb:B4DII8 uniprotkb:B2R5V1 uniprotkb:D3DSD1 uniprotkb:D3DSD2 uniprotkb:D3DSD3 ensembl:ENSP00000284981.4 |
| Alternative identifier for interactor B | intact:EBI-1752330 uniprotkb:D7UT47 uniprotkb:Q8TET3 intact:EBI-28969573 |
| Aliases for A | psi-mi:a4_human(display_long) uniprotkb:APP(gene name) psi-mi:APP(display_short) uniprotkb:A4(gene name synonym) uniprotkb:AD1(gene name synonym) uniprotkb:Alzheimer disease amyloid protein(gene name synonym) uniprotkb:ABPP(gene name synonym) uniprotkb:PreA4(gene name synonym) uniprotkb:Cerebral vascular amyloid peptide(gene name synonym) uniprotkb:Protease nexin-II(gene name synonym) uniprotkb:APPI(gene name synonym) uniprotkb:Amyloid precursor protein(gene name synonym) uniprotkb:Amyloid-beta A4 protein(gene name synonym) uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym) uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym) |
| Aliases for B | psi-mi:shan3_human(display_long) uniprotkb:SHANK3(gene name) psi-mi:SHANK3(display_short) uniprotkb:KIAA1650(gene name synonym) uniprotkb:PSAP2(gene name synonym) uniprotkb:Proline-rich synapse-associated protein 2(gene name synonym) uniprotkb:PROSAP2(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0398"(two hybrid pooling approach) |
| First author | Sakai et al. (2011) |
| Identifier of the publication | doi:10.1126/scitranslmed.3002166 pubmed:21653829 imex:IM-28561 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-26513794 imex:IM-28561-1055 |
| Confidence score | intact-miscore:0.37 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:ST2 comment:"\"Library for Y2H screening used: human brain\"" curation depth:imex curation full coverage:Only protein-protein interactions dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\"" |
| NCBI Taxonomy identifier for the host organism | taxid:4932(yeasx) taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") |
| Parameters of the interaction | - |
| Creation date | 2020/10/05 |
| Update date | 2024/11/12 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | sufficient binding region:791-1222 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Nucleotide sequence identification |
| Participant identification method for interactor B | Nucleotide sequence identification |