| Unique identifier for interactor A | uniprotkb:Q05397 |
| Unique identifier for interactor B | uniprotkb:Q824H6 |
| Alternative identifier for interactor A | intact:EBI-702142 intact:EBI-11047590 uniprotkb:B4E2N6 uniprotkb:F5H4S4 ensembl:ENSP00000429474.1 ensembl:ENSP00000429911.1 uniprotkb:J3QT16 uniprotkb:Q8IYN9 uniprotkb:Q14291 uniprotkb:Q9UD85 |
| Alternative identifier for interactor B | intact:EBI-26494126 |
| Aliases for A | psi-mi:fak1_human(display_long) uniprotkb:PTK2(gene name) psi-mi:PTK2(display_short) uniprotkb:FAK(gene name synonym) uniprotkb:FAK1(gene name synonym) uniprotkb:pp125FAK(gene name synonym) uniprotkb:Protein-tyrosine kinase 2(gene name synonym) uniprotkb:Focal adhesion kinase-related nonkinase(gene name synonym) uniprotkb:Protein phosphatase 1 regulatory subunit 71(gene name synonym) uniprotkb:p125FAK(gene name synonym) |
| Aliases for B | psi-mi:q824h6_chlcv(display_long) uniprotkb:CCA_00170(locus name) |
| Interaction detection methods | psi-mi:"MI:0018"(two hybrid) |
| First author | Thwaites et al. (2014) |
| Identifier of the publication | pubmed:25193659 imex:IM-28529 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:227941(Chlamydia caviae) taxid:227941("Chlamydophila caviae (strain ATCC VR-813 / DSM 19441 / GPIC)") |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-26498300 imex:IM-28529-4 |
| Confidence score | intact-miscore:0.54 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:fig. 4f comment:"\"TarP-LD interaction with FAT was evaluated and directly compared with paxillin LD2 and TarP-mutLD. A positive control Cya18-Zip/Cya25-Zip was included. By measuring β-gal production, it was clear that Cya18-TarP-LD/Cya25-FAT or Cya18-Pax-LD2/Cya25-FAT-co-expressing bacteria exhibited activity that differed significantly from the negative control strain (Fig. 4F; p < 0.01 ANOVA and Tukey-Kramer post hoc test). Importantly, the Leu-to-Ala substitution mutant did not interact with FAT.\"" full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:316385(ecodh) taxid:316385("Escherichia coli (strain K12 / DH10B)") |
| Parameters of the interaction | - |
| Creation date | 2020/11/12 |
| Update date | 2020/12/02 |
| negative Boolean value | false |
| Feature(s) for interactor A | binding-associated region:904..904-1052..1052 |
| Feature(s) for interactor B | binding-associated region:640-740 mutation disrupting interaction:660-660,663-664 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |