Curation Details
Interaction ID: IM-28526-3

Unique identifier for interactor Auniprotkb:Q6NZM9
Unique identifier for interactor Buniprotkb:Q80VC9
Alternative identifier for interactor Aintact:EBI-646397
uniprotkb:Q3TRZ9
uniprotkb:Q3U2J3
uniprotkb:Q3V3Y4
ensembl:ENSMUSP00000008995.9
ensembl:ENSMUSP00000095249.4
Alternative identifier for interactor Bintact:EBI-2125556
uniprotkb:Q5DTW9
uniprotkb:Q8BUZ0
uniprotkb:E9Q5B0
uniprotkb:U5LGR7
uniprotkb:U5LGS1
uniprotkb:U5LGS5
uniprotkb:U5LGT0
uniprotkb:U5LHT8
uniprotkb:U5LHU4
uniprotkb:U5LHW1
uniprotkb:U5LHW4
uniprotkb:U5LHW9
uniprotkb:U5LK15
uniprotkb:U5LK19
uniprotkb:U5LK24
uniprotkb:U5LK70
uniprotkb:U5LK74
uniprotkb:U5LK79
ensembl:ENSMUSP00000058958.8
Aliases for Apsi-mi:hdac4_mouse(display_long)
uniprotkb:Hdac4(gene name)
psi-mi:Hdac4(display_short)
Aliases for Bpsi-mi:camp3_mouse(display_long)
uniprotkb:Marshalin(gene name synonym)
uniprotkb:Camsap3(gene name)
psi-mi:Camsap3(display_short)
uniprotkb:Protein Nezha(gene name synonym)
uniprotkb:Kiaa1543(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorFederspiel et al. (2019)
Identifier of the publicationimex:IM-28526
pubmed:31040226
NCBI Taxonomy identifier for interactor Ataxid:10090(mouse)
taxid:10090(Mus musculus)
NCBI Taxonomy identifier for interactor Btaxid:10090(mouse)
taxid:10090(Mus musculus)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26472137
imex:IM-28526-3
Confidence scoreintact-miscore:0.35
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST2
comment:"\"Q140 mice, 10 months old were used for this experiment. \\"the Q20 mouse was used as a “normal” condition, as this repeat length represents a non-disease causing polyQ repeat, and the Q140 mouse represented an HD disease condition.\\"\""
comment:"\"we used a SAINT score cutoff of ≥0.8 for isolations of Hdac4 in the whole brain for the Q20 2- and 10-month data and the Q140 2-month data (28). For the Q140 10-month data, we observed an overall increase in the number of proteins that passed this cutoff. Given the possibility that some of these interactions may derive non-specifically from the increased aggregation present in these symptomatic brains, we used a more stringent cutoff of ≥0.95 when analyzing these data.\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:10090(mouse-brain)
taxid:10090(Mus musculus brain)
Parameters of the interaction-
Creation date2020/11/24
Update date2023/01/11
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AIdentification by mass spectrometry
Participant identification method for interactor BIdentification by mass spectrometry