| Unique identifier for interactor A | uniprotkb:Q6NZM9 |
| Unique identifier for interactor B | uniprotkb:Q08460 |
| Alternative identifier for interactor A | intact:EBI-646397 uniprotkb:Q3TRZ9 uniprotkb:Q3U2J3 uniprotkb:Q3V3Y4 ensembl:ENSMUSP00000008995.9 ensembl:ENSMUSP00000095249.4 |
| Alternative identifier for interactor B | intact:EBI-1633915 uniprotkb:Q64703 uniprotkb:Q8VHF1 uniprotkb:Q9R196 |
| Aliases for A | psi-mi:hdac4_mouse(display_long) uniprotkb:Hdac4(gene name) psi-mi:Hdac4(display_short) |
| Aliases for B | psi-mi:kcma1_mouse(display_long) uniprotkb:Kcnma1(gene name) psi-mi:Kcnma1(display_short) uniprotkb:Kcnma(gene name synonym) uniprotkb:Calcium-activated potassium channel, subfamily M subunit alpha-1(gene name synonym) uniprotkb:Maxi K channel(gene name synonym) uniprotkb:BK channel(gene name synonym) uniprotkb:"K(VCA)alpha"(gene name synonym) uniprotkb:BKCA alpha(gene name synonym) uniprotkb:KCa1.1(gene name synonym) uniprotkb:Slowpoke homolog(gene name synonym) uniprotkb:Slo-alpha(gene name synonym) uniprotkb:Slo1(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0006"(anti bait coimmunoprecipitation) |
| First author | Federspiel et al. (2019) |
| Identifier of the publication | imex:IM-28526 pubmed:31040226 |
| NCBI Taxonomy identifier for interactor A | taxid:10090(mouse) taxid:10090(Mus musculus) |
| NCBI Taxonomy identifier for interactor B | taxid:10090(mouse) taxid:10090(Mus musculus) |
| Interaction types | psi-mi:"MI:0914"(association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-26471532 imex:IM-28526-21 |
| Confidence score | intact-miscore:0.35 |
| Complex expansion | psi-mi:"MI:1060"(spoke expansion) |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:ST2 comment:"\"Q20 mice, 10 months old were used for this experiment. \\"the Q20 mouse was used as a “normal” condition, as this repeat length represents a non-disease causing polyQ repeat, and the Q140 mouse represented an HD disease condition.\\"\"" comment:"\"we used a SAINT score cutoff of ≥0.8 for isolations of Hdac4 in the whole brain for the Q20 2- and 10-month data and the Q140 2-month data (28). For the Q140 10-month data, we observed an overall increase in the number of proteins that passed this cutoff. Given the possibility that some of these interactions may derive non-specifically from the increased aggregation present in these symptomatic brains, we used a more stringent cutoff of ≥0.95 when analyzing these data.\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:10090(mouse-brain) taxid:10090(Mus musculus brain) |
| Parameters of the interaction | - |
| Creation date | 2020/11/24 |
| Update date | 2020/11/25 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Identification by mass spectrometry |
| Participant identification method for interactor B | Identification by mass spectrometry |