Curation Details
Interaction ID: IM-28502-10

Unique identifier for interactor Auniprotkb:Q5U458
Unique identifier for interactor Buniprotkb:P11142
Alternative identifier for interactor Aintact:EBI-772487
ensembl:ENSMUSP00000051643.5
uniprotkb:A2A8C9
uniprotkb:Q8BP83
uniprotkb:Q8C1Z4
uniprotkb:Q8C6U5
Alternative identifier for interactor Bintact:EBI-351896
ensembl:ENSP00000437125.1
ensembl:ENSP00000227378.3
ensembl:ENSP00000432083.1
uniprotkb:Q9H3R6
Aliases for Apsi-mi:djc11_mouse(display_long)
uniprotkb:Dnajc11(gene name)
psi-mi:Dnajc11(display_short)
Aliases for Bpsi-mi:hsp7c_human(display_long)
uniprotkb:HSPA8(gene name)
psi-mi:HSPA8(display_short)
uniprotkb:HSC70(gene name synonym)
uniprotkb:HSP73(gene name synonym)
uniprotkb:HSPA10(gene name synonym)
uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)
uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorViolitzi et al. (2019)
Identifier of the publicationpubmed:31550165
imex:IM-28502
NCBI Taxonomy identifier for interactor Ataxid:10090(mouse)
taxid:10090(Mus musculus)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26453996
imex:IM-28502-10
Confidence scoreintact-miscore:0.35
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:figure 2D, Supp. table 7
comment:"\"Putative DNAJC11 protein interactions have been further prioritized with the MiST software, which scores large-scale affinity purification mass spectrometry data sets based on the prey’s abundance, reproducibility, and specificity. MiST analysis (MiST score >0.75) revealed 26 high-confidence DNAJC11 interactors.\""
comment:"\"Deletion of the DUF3395 domain (amino acids 410 to 559) abolishes the majority of DNAJC11 interactions;MiST analysis prioritized (retained) only HSPA1A and HSPA8.\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293ft)
taxid:9606(Homo sapiens HEK293FT embryonic kidney cell)
Parameters of the interaction-
Creation date2020/11/17
Update date2020/11/24
negative Boolean valuefalse
Feature(s) for interactor Aflag tag:c-c
sufficient binding region:1-409
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AMultidimensional protein identification technology
Participant identification method for interactor BMultidimensional protein identification technology