Curation Details
Interaction ID: IM-28496-1

Unique identifier for interactor Auniprotkb:P50897
Unique identifier for interactor Buniprotkb:B7XGA6
Alternative identifier for interactor Aintact:EBI-1237011
intact:EBI-2859371
uniprotkb:Q6FGQ4
uniprotkb:B4DY24
ensembl:ENSP00000432053.1
ensembl:ENSP00000493153.1
Alternative identifier for interactor Bintact:EBI-26446220
Aliases for Apsi-mi:ppt1_human(display_long)
uniprotkb:PPT1(gene name)
psi-mi:PPT1(display_short)
uniprotkb:PPT(gene name synonym)
uniprotkb:Palmitoyl-protein hydrolase 1(gene name synonym)
uniprotkb:CLN1(gene name synonym)
Aliases for Bpsi-mi:b7xga6_mouse(display_long)
uniprotkb:Alpl(gene name)
psi-mi:Alpl(display_short)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorSapir et al. (2018)
Identifier of the publicationimex:IM-28496
pubmed:30918483
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:10090(mouse)
taxid:10090(Mus musculus)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26446811
imex:IM-28496-1
Confidence scoreintact-miscore:0.35
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST2
comment:"\"To identify PPT1 binding proteins, we affinity purified GFP-PPT1 binding proteins using brain lysates derived from Ppt1−/− or wild type in comparison with GFP proteins. The list includes peptides which were statistically significant either in lysates derived from wild type brains and/or in lysates derived from Ppt1−/− brains, for 96 of the peptides, protein symbols could be assigned (Supplementary Table S1). Overall, we identified 64 proteins as PPT1 interacting proteins\""
curation depth:imex curation
full coverage:Only protein-protein interactions
dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2020/11/13
Update date2024/11/28
negative Boolean valuefalse
Feature(s) for interactor Agreen fluorescent protein tag:?-?
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AIdentification by mass spectrometry
Participant identification method for interactor BIdentification by mass spectrometry