| Unique identifier for interactor A | uniprotkb:Q8VSP9 |
| Unique identifier for interactor B | uniprotkb:P28482 |
| Alternative identifier for interactor A | intact:EBI-6506625 uniprotkb:Q2ET10 uniprotkb:Q2ET14 uniprotkb:Q6XW10 uniprotkb:Q7BEG0 uniprotkb:Q99Q87 |
| Alternative identifier for interactor B | intact:EBI-959949 uniprotkb:A8CZ64 ensembl:ENSP00000215832.7 ensembl:ENSP00000381803.3 |
| Aliases for A | psi-mi:ospf_shifl(display_long) uniprotkb:ospF(gene name) psi-mi:ospF(display_short) uniprotkb:mkaD(gene name synonym) uniprotkb:Effector protein OspF(gene name synonym) uniprotkb:pWR501_0013(orf name) uniprotkb:SFLP011(orf name) uniprotkb:CP0010(locus name) |
| Aliases for B | psi-mi:mk01_human(display_long) uniprotkb:MAPK1(gene name) psi-mi:MAPK1(display_short) uniprotkb:ERK2(gene name synonym) uniprotkb:PRKM1(gene name synonym) uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym) uniprotkb:Mitogen-activated protein kinase 2(gene name synonym) uniprotkb:MAP kinase isoform p42(gene name synonym) uniprotkb:ERT1(gene name synonym) uniprotkb:PRKM2(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0415"(enzymatic study) |
| First author | Zhu et al. (2007) |
| Identifier of the publication | imex:IM-28467 pubmed:18060821 |
| NCBI Taxonomy identifier for interactor A | taxid:623(shifl) taxid:623(Shigella flexneri) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0414"(enzymatic reaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-26435196 imex:IM-28467-21 |
| Confidence score | intact-miscore:0.67 |
| Complex expansion | - |
| Biological role A | Enzyme |
| Biological role B | Enzyme target |
| Experimental role A | Unspecified role |
| Experimental role B | Unspecified role |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:fig.1 a,b,c comment:"\"As shown in Figure 1B, a mass loss of 98 dalton from the Erk2 phosphopeptide was observed as a result of OspF treatment, and an additional mass of 77 dalton was regained after subsequent incubation with cysteamine. Results of tandem mass spectrometry analysis indicate that the 77 dalton mass increase occurred on the “threonine” residue (Figure 1C), consistent with the hypothesized addition reaction of the unsaturated Cα = Cβ bond with cysteamine\"" full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2020/10/13 |
| Update date | 2020/10/29 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | binding-associated region:179-191 modified L-threonine residue:185-185 O4'-phospho-L-tyrosine:187-187 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Identification by mass spectrometry |
| Participant identification method for interactor B | Identification by mass spectrometry |