Curation Details
Interaction ID: IM-28455-5

Unique identifier for interactor Auniprotkb:B7UR60
Unique identifier for interactor Buniprotkb:Q13428
Alternative identifier for interactor Aintact:EBI-25435618
Alternative identifier for interactor Bintact:EBI-396105
uniprotkb:Q6SC72
uniprotkb:Q7Z5W9
uniprotkb:Q96A52
uniprotkb:Q99408
uniprotkb:Q99860
uniprotkb:A0JLU0
uniprotkb:B4E111
ensembl:ENSP00000367028.4
ensembl:ENSP00000421655.2
intact:EBI-28974716
Aliases for Apsi-mi:b7ur60_eco27(display_long)
uniprotkb:E2348C_1442(locus name)
Aliases for Bpsi-mi:tcof_human(display_long)
uniprotkb:TCOF1(gene name)
psi-mi:TCOF1(display_short)
uniprotkb:Treacher Collins syndrome protein(gene name synonym)
Interaction detection methodspsi-mi:"MI:0398"(two hybrid pooling approach)
First authorLee et al. (2008)
Identifier of the publicationpubmed:17979986
imex:IM-28455
NCBI Taxonomy identifier for interactor Ataxid:574521(eco27)
taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26377654
imex:IM-28455-5
Confidence scoreintact-miscore:0.49
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:table 1
comment:To identify potential eukaryotic interacting partners of EspI, we performed a Y2HS screen of a pretransformed HeLa cDNA library using the full-length EspI from EPEC E2348/69 as bait.
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:4932(yeasx)
taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
Parameters of the interaction-
Creation date2020/10/13
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bbinding-associated region:356-513
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification