| Unique identifier for interactor A | uniprotkb:P10636 |
| Unique identifier for interactor B | uniprotkb:Q96CW1 |
| Alternative identifier for interactor A | intact:EBI-366182 uniprotkb:P18518 uniprotkb:Q14799 uniprotkb:Q15549 uniprotkb:Q15550 uniprotkb:Q15551 uniprotkb:Q1RMF6 uniprotkb:Q53YB1 uniprotkb:Q5CZI7 uniprotkb:Q5XWF0 uniprotkb:Q6QT54 uniprotkb:Q9UDJ3 uniprotkb:Q9UMH0 uniprotkb:Q9UQ96 ensembl:ENSP00000458742.1 |
| Alternative identifier for interactor B | intact:EBI-297683 uniprotkb:D3DNT1 ensembl:ENSP00000292807.5 uniprotkb:A6NE12 uniprotkb:P20172 uniprotkb:P53679 |
| Aliases for A | psi-mi:tau_human(display_long) uniprotkb:MAPT(gene name) psi-mi:MAPT(display_short) uniprotkb:MTBT1(gene name synonym) uniprotkb:TAU(gene name synonym) uniprotkb:Neurofibrillary tangle protein(gene name synonym) uniprotkb:Paired helical filament-tau(gene name synonym) uniprotkb:MAPTL(gene name synonym) |
| Aliases for B | psi-mi:ap2m1_human(display_long) uniprotkb:Adaptor protein complex AP-2 subunit mu(gene name synonym) uniprotkb:AP-2 mu chain(gene name synonym) uniprotkb:AP2M1(gene name) psi-mi:AP2M1(display_short) uniprotkb:CLAPM1(gene name synonym) uniprotkb:KIAA0109(gene name synonym) uniprotkb:Adaptin-mu2(gene name synonym) uniprotkb:Plasma membrane adaptor AP-2 50 kDa protein(gene name synonym) uniprotkb:HA2 50 kDa subunit(gene name synonym) uniprotkb:Clathrin coat assembly protein AP50(gene name synonym) uniprotkb:Clathrin coat-associated protein AP50(gene name synonym) uniprotkb:Clathrin assembly protein complex 2 mu medium chain(gene name synonym) uniprotkb:Adaptor-related protein complex 2 subunit mu(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0006"(anti bait coimmunoprecipitation) |
| First author | Sinsky et al. (2020) |
| Identifier of the publication | imex:IM-28438 pubmed:32357304 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0914"(association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-26374285 imex:IM-28438-3 |
| Confidence score | intact-miscore:0.35 |
| Complex expansion | psi-mi:"MI:1060"(spoke expansion) |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:F3 SF4C-D comment:"\"Co-IP from human cerebral cortex confirmed five out of eight analyzed proteins: Ap2m1, Atp1a1, Baiap2, Nptx1, and Psmd2 in both AD and control brains, and two of them, Ap2m1 and Atp1a1, were immunoprecipitated from AD brain in higher amounts as compared to controls.\"" dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases. dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-brain-cortex) taxid:9606(Homo sapiens brain cortex) |
| Parameters of the interaction | - |
| Creation date | 2020/10/19 |
| Update date | 2020/10/19 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |