Curation Details
Interaction ID: IM-28438-25

Unique identifier for interactor Auniprotkb:P10636-8
Unique identifier for interactor Buniprotkb:Q13200
Alternative identifier for interactor Aintact:EBI-366233
intact:EBI-7470331
intact:MINT-134477
intact:EBI-7470384
intact:EBI-7638179
intact:EBI-7638125
intact:EBI-7638230
intact:EBI-7638364
intact:EBI-7961077
intact:EBI-7470086
intact:EBI-7637965
intact:EBI-7638329
intact:EBI-7470156
intact:EBI-7470185
intact:EBI-7470243
intact:EBI-7638049
intact:EBI-7470111
intact:EBI-7637861
ensembl:ENSP00000303214.7
ensembl:ENSP00000460965.1
ensembl:ENSP00000477703.1
ensembl:ENSP00000484491.1
ensembl:ENSP00000487819.1
ensembl:ENSP00000515600.1
Alternative identifier for interactor Bintact:EBI-357648
ensembl:ENSP00000310129.4
uniprotkb:Q53XQ4
uniprotkb:B4DX07
uniprotkb:B4DXY1
uniprotkb:E7EW34
uniprotkb:E9PCS3
uniprotkb:Q12932
uniprotkb:Q15321
uniprotkb:Q96I12
Aliases for Apsi-mi:p10636-8(display_long)
uniprotkb:Tau-4(isoform synonym)
uniprotkb:MAPT(gene name)
psi-mi:MAPT(display_short)
uniprotkb:MAPTL(gene name synonym)
uniprotkb:MTBT1(gene name synonym)
uniprotkb:TAU(gene name synonym)
uniprotkb:Neurofibrillary tangle protein(gene name synonym)
uniprotkb:Paired helical filament-tau(gene name synonym)
uniprotkb:2N4R(isoform synonym)
Aliases for Bpsi-mi:psmd2_human(display_long)
uniprotkb:PSMD2(gene name)
psi-mi:PSMD2(display_short)
uniprotkb:TRAP2(gene name synonym)
uniprotkb:26S proteasome regulatory subunit RPN1(gene name synonym)
uniprotkb:26S proteasome regulatory subunit S2(gene name synonym)
uniprotkb:26S proteasome subunit p97(gene name synonym)
uniprotkb:Tumor necrosis factor type 1 receptor-associated protein 2(gene name synonym)
uniprotkb:Protein 55.11(gene name synonym)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorSinsky et al. (2020)
Identifier of the publicationimex:IM-28438
pubmed:32357304
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26374399
imex:IM-28438-25
Confidence scoreintact-miscore:0.71
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F4D
comment:"\"Overexpression of pathogenic human truncated tau (151–391/4R)\""
dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.
dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-sh_sy5y)
taxid:9606(Homo sapiens SH-SY5Y cell)
Parameters of the interaction-
Creation date2020/10/19
Update date2020/10/19
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:151-391
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AImmunostaining
Participant identification method for interactor BImmunostaining