Curation Details
Interaction ID: IM-28438-1

Unique identifier for interactor Auniprotkb:P19332
Unique identifier for interactor Buniprotkb:P47971
Alternative identifier for interactor Aintact:EBI-7080713
uniprotkb:Q63567
uniprotkb:Q63677
uniprotkb:Q9QW06
intact:MINT-1037362
Alternative identifier for interactor Bintact:EBI-26373006
ensembl:ENSRNOP00000005067.6
ensembl:ENSRNOP00055045272
ensembl:ENSRNOP00060040038
ensembl:ENSRNOP00065004836
Aliases for Apsi-mi:tau_rat(display_long)
uniprotkb:Mapt(gene name)
psi-mi:Mapt(display_short)
uniprotkb:Mtapt(gene name synonym)
uniprotkb:Tau(gene name synonym)
uniprotkb:Neurofibrillary tangle protein(gene name synonym)
uniprotkb:Paired helical filament-tau(gene name synonym)
Aliases for Bpsi-mi:nptx1_rat(display_long)
uniprotkb:47 kDa taipoxin-binding protein(gene name synonym)
uniprotkb:Neuronal pentraxin I(gene name synonym)
uniprotkb:Nptx1(gene name)
psi-mi:Nptx1(display_short)
Interaction detection methodspsi-mi:"MI:0030"(cross-linking study)
First authorSinsky et al. (2020)
Identifier of the publicationimex:IM-28438
pubmed:32357304
NCBI Taxonomy identifier for interactor Ataxid:10116(rat)
taxid:10116("Rattus norvegicus (Rat)")
NCBI Taxonomy identifier for interactor Btaxid:10116(rat)
taxid:10116("Rattus norvegicus (Rat)")
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26374040
imex:IM-28438-1
Confidence scoreintact-miscore:0.46
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F2 ST3
comment:"\"Identified proteins were screened for known tau-interacting partners using the Integrated Inter-actions Database (IID), annotated as previously detected or predicted tau partners in human, rat, or mouse (Table S3) and ranked as low, medium, or high confidence interactions (see ranking criteria,Table S2). Using these criteria, we obtained a total of 175 high confidence tau interactions.\""
comment:"\"Isolation of in vivo cross-linked tau protein complexes was performed by tandem affinity chromatography with three different mAb’s in the following order: DC18, DC190, and DC25.\""
curation depth:imex curation
full coverage:Only protein-protein interactions
dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.
dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease
NCBI Taxonomy identifier for the host organismtaxid:10116(rat-brain)
taxid:10116(Rattus norvegicus brain)
Parameters of the interaction-
Creation date2020/10/19
Update date2020/10/19
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AIdentification by mass spectrometry
Participant identification method for interactor BIdentification by mass spectrometry