| Unique identifier for interactor A | uniprotkb:P19332 |
| Unique identifier for interactor B | uniprotkb:P62828 |
| Alternative identifier for interactor A | intact:EBI-7080713 uniprotkb:Q63567 uniprotkb:Q63677 uniprotkb:Q9QW06 intact:MINT-1037362 |
| Alternative identifier for interactor B | intact:EBI-286590 uniprotkb:P17080 uniprotkb:P28746 uniprotkb:P28747 uniprotkb:Q9CSP3 uniprotkb:Q9CWI7 uniprotkb:Q9CZA2 uniprotkb:Q9UEU9 uniprotkb:Q9UDJ5 ensembl:ENSRNOP00000001247.4 |
| Aliases for A | psi-mi:tau_rat(display_long) uniprotkb:Mapt(gene name) psi-mi:Mapt(display_short) uniprotkb:Mtapt(gene name synonym) uniprotkb:Tau(gene name synonym) uniprotkb:Neurofibrillary tangle protein(gene name synonym) uniprotkb:Paired helical filament-tau(gene name synonym) |
| Aliases for B | psi-mi:ran_rat(display_long) uniprotkb:GTPase Ran(gene name synonym) uniprotkb:Ras-related nuclear protein(gene name synonym) uniprotkb:Ras-like protein TC4(gene name synonym) uniprotkb:Ran(gene name) psi-mi:Ran(display_short) |
| Interaction detection methods | psi-mi:"MI:0030"(cross-linking study) |
| First author | Sinsky et al. (2020) |
| Identifier of the publication | imex:IM-28438 pubmed:32357304 |
| NCBI Taxonomy identifier for interactor A | taxid:10116(rat) taxid:10116("Rattus norvegicus (Rat)") |
| NCBI Taxonomy identifier for interactor B | taxid:10116(rat) taxid:10116("Rattus norvegicus (Rat)") |
| Interaction types | psi-mi:"MI:0914"(association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-26374040 imex:IM-28438-1 |
| Confidence score | intact-miscore:0.46 |
| Complex expansion | psi-mi:"MI:1060"(spoke expansion) |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:F2 ST3 comment:"\"Identified proteins were screened for known tau-interacting partners using the Integrated Inter-actions Database (IID), annotated as previously detected or predicted tau partners in human, rat, or mouse (Table S3) and ranked as low, medium, or high confidence interactions (see ranking criteria,Table S2). Using these criteria, we obtained a total of 175 high confidence tau interactions.\"" comment:"\"Isolation of in vivo cross-linked tau protein complexes was performed by tandem affinity chromatography with three different mAb’s in the following order: DC18, DC190, and DC25.\"" curation depth:imex curation full coverage:Only protein-protein interactions dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases. dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease |
| NCBI Taxonomy identifier for the host organism | taxid:10116(rat-brain) taxid:10116(Rattus norvegicus brain) |
| Parameters of the interaction | - |
| Creation date | 2020/10/19 |
| Update date | 2025/06/30 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Identification by mass spectrometry |
| Participant identification method for interactor B | Identification by mass spectrometry |