Curation Details
Interaction ID: IM-28371-13

Unique identifier for interactor Auniprotkb:B3CRR2
Unique identifier for interactor Buniprotkb:Q14974
Alternative identifier for interactor Aintact:EBI-26357571
Alternative identifier for interactor Bintact:EBI-286758
uniprotkb:Q14637
uniprotkb:Q96J27
uniprotkb:Q53XN2
uniprotkb:B7ZAV6
uniprotkb:D3DTT3
ensembl:ENSP00000290158.3
ensembl:ENSP00000464042.2
intact:EBI-28976864
Aliases for Apsi-mi:b3crr2_oriti(display_long)
uniprotkb:OTT_0753(locus name)
Aliases for Bpsi-mi:imb1_human(display_long)
uniprotkb:Karyopherin subunit beta-1(gene name synonym)
uniprotkb:Nuclear factor p97(gene name synonym)
uniprotkb:Importin-90(gene name synonym)
uniprotkb:KPNB1(gene name)
psi-mi:KPNB1(display_short)
uniprotkb:NTF97(gene name synonym)
uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorEvans et al. (2018)
Identifier of the publicationimex:IM-28371
pubmed:29734393
NCBI Taxonomy identifier for interactor Ataxid:334380(Rickettsia tsutsugamushi)
taxid:334380("Orientia tsutsugamushi (strain Ikeda)")
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26357857
imex:IM-28371-13
Confidence scoreintact-miscore:0.50
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F15
comment:"\"With the exception of ankyrin repeat 1, Flag-tagged Ank1 required an intact ankyrin repeat domain and the ISR to optimally interact with importin β1 (Fig 15).\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hela)
taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2020/09/23
Update date2024/11/07
negative Boolean valuefalse
Feature(s) for interactor Asufficient binding region:56-157,167-201
flag tag:n-n
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot