| Unique identifier for interactor A | uniprotkb:P07355 |
| Unique identifier for interactor B | uniprotkb:Q15599 |
| Alternative identifier for interactor A | intact:EBI-352622 uniprotkb:Q567R4 uniprotkb:Q96DD5 intact:EBI-2211824 uniprotkb:Q8TBV2 uniprotkb:Q6N0B3 uniprotkb:Q9UDH8 ensembl:ENSP00000379342.3 ensembl:ENSP00000387545.3 ensembl:ENSP00000411352.2 ensembl:ENSP00000452858.2 ensembl:ENSP00000452895.2 ensembl:ENSP00000452981.2 ensembl:ENSP00000453694.2 ensembl:ENSP00000453859.2 ensembl:ENSP00000503447.1 ensembl:ENSP00000503757.1 ensembl:ENSP00000503855.1 ensembl:ENSP00000504035.1 ensembl:ENSP00000504164.1 |
| Alternative identifier for interactor B | intact:EBI-1149760 uniprotkb:O00272 uniprotkb:O00556 uniprotkb:Q3KQY7 uniprotkb:D3DU84 uniprotkb:D3DU85 uniprotkb:H3BSV6 intact:EBI-15579694 ensembl:ENSP00000408005.2 |
| Aliases for A | psi-mi:anxa2_human(display_long) uniprotkb:ANXA2(gene name) psi-mi:ANXA2(display_short) uniprotkb:ANX2(gene name synonym) uniprotkb:ANX2L4(gene name synonym) uniprotkb:CAL1H(gene name synonym) uniprotkb:LPC2D(gene name synonym) uniprotkb:Annexin-2(gene name synonym) uniprotkb:Annexin II(gene name synonym) uniprotkb:Lipocortin II(gene name synonym) uniprotkb:Calpactin I heavy chain(gene name synonym) uniprotkb:Chromobindin-8(gene name synonym) uniprotkb:p36(gene name synonym) uniprotkb:Protein I(gene name synonym) uniprotkb:Placental anticoagulant protein IV(gene name synonym) uniprotkb:Calpactin-1 heavy chain(gene name synonym) |
| Aliases for B | psi-mi:nhrf2_human(display_long) uniprotkb:NHERF2(gene name) psi-mi:NHERF2(display_short) uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym) uniprotkb:SLC9A3R2(gene name synonym) uniprotkb:SRY-interacting protein 1(gene name synonym) uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym) uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym) uniprotkb:Tyrosine kinase activator protein 1(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0416"(fluorescence microscopy) |
| First author | Munera et al. (2012) |
| Identifier of the publication | pubmed:22587461 imex:IM-28348 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0403"(colocalization) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-25829123 imex:IM-28348-1 |
| Confidence score | intact-miscore:0.65 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:fig 1a comment:"\"Immunofluorescence using anti-HA antibodies combined with the GFP signal revealed partial co-localization of NHERF2 and AnxA2 in 70–80% of examined uninfected cells (Figure 1; uninfected). In order to determine the localization of NHERF2 and AnxA2 during EPEC infection, HeLaNHERF2 cells ectopically expressing AnxA2 were infected with wild-type EPEC strain E2348/69 and E2348/69ΔescN (encoding the ATPase) mutant, defective in T3SS, as a control. This has shown that both NHERF2 and AnxA2 are recruited by wild-type EPEC and co-localized at the bacterial attachment sites in 90–100% of examined cells.\"" stimulant:EPEC infection curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-hela) taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell) |
| Parameters of the interaction | - |
| Creation date | 2020/09/08 |
| Update date | 2020/09/15 |
| negative Boolean value | false |
| Feature(s) for interactor A | green fluorescent protein tag:?-? |
| Feature(s) for interactor B | ha tag:?-? |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Tag visualisation by fluorescence |
| Participant identification method for interactor B | Immunostaining |