| Unique identifier for interactor A | uniprotkb:P55211 |
| Unique identifier for interactor B | uniprotkb:Q8XAL7 |
| Alternative identifier for interactor A | intact:EBI-516799 uniprotkb:Q53Y70 uniprotkb:Q5JRU9 uniprotkb:Q5UGI1 uniprotkb:B4E1A3 ensembl:ENSP00000330237.5 uniprotkb:O95348 uniprotkb:Q92852 uniprotkb:Q9BQ62 uniprotkb:Q9UEQ3 uniprotkb:Q9UIJ8 |
| Alternative identifier for interactor B | intact:EBI-10039292 uniprotkb:Q7AEM9 |
| Aliases for A | psi-mi:casp9_human(display_long) uniprotkb:ICE-like apoptotic protease 6(gene name synonym) uniprotkb:Apoptotic protease Mch-6(gene name synonym) uniprotkb:Apoptotic protease-activating factor 3(gene name synonym) uniprotkb:CASP9(gene name) psi-mi:CASP9(display_short) uniprotkb:MCH6(gene name synonym) |
| Aliases for B | psi-mi:nlef_eco57(display_long) uniprotkb:nleF(gene name) psi-mi:nleF(display_short) uniprotkb:Non-LEE-encoded type III effector F(gene name synonym) uniprotkb:Z6020.1(locus name) uniprotkb:ECs1815(locus name) |
| Interaction detection methods | psi-mi:"MI:2318"(force measurement) |
| First author | Blasche et al. (2012) |
| Identifier of the publication | pubmed:23516580 imex:IM-28332 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:83334(eco57) taxid:83334("Escherichia coli O157:H7") |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-25827349 imex:IM-28332-5 |
| Confidence score | intact-miscore:0.72 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:fig. 1c comment:"\"The affinity constant (Kd) of NleF binding to immobilized caspase-9 as measured by surface acoustic wave (SAW) technology is ∼39 nM.\"" comment:"\"Binding kinetic and affinity was analysed on sam®5 BLUE and sam®5 GREEN instruments (SAW Instruments GmbH, Bonn, Germany). Both instruments use the \\"surface acoustic wave\\"-principle for label-free analysis of molecular binding in a flow-through system as described in Perpeet et al. (2006)\"" full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | kd:39.0x10^-9(molar) |
| Creation date | 2020/09/08 |
| Update date | 2020/09/11 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |