Curation Details
Interaction ID: IM-28236-172

Unique identifier for interactor Auniprotkb:P03427
Unique identifier for interactor Buniprotkb:P15659
Alternative identifier for interactor Aintact:EBI-8430745
intact:MINT-8081619
Alternative identifier for interactor Bintact:EBI-8431752
intact:MINT-8081657
Aliases for Apsi-mi:pb2_i33a0(display_long)
uniprotkb:PB2(gene name)
psi-mi:PB2(display_short)
uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)
Aliases for Bpsi-mi:pa_i33a0(display_long)
uniprotkb:PA(gene name)
psi-mi:PA(display_short)
uniprotkb:RNA-directed RNA polymerase subunit P2(gene name synonym)
Interaction detection methodspsi-mi:"MI:1203"(split luciferase complementation)
First authorMunier et al. (2013)
Identifier of the publicationpubmed:23816991
imex:IM-28236
doi:10.1074/mcp.m113.028688
NCBI Taxonomy identifier for interactor Ataxid:381518(i33a0)
taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")
NCBI Taxonomy identifier for interactor Btaxid:381518(i33a0)
taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-25819523
imex:IM-28236-172
Confidence scoreintact-miscore:0.55
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F2A
comment:A strong and dose-dependent reduction of luciferase activities was observed in the presence of ribavirin
antagonist:100 µM ribavidin
curation depth:imex curation
dataset:Virus - Publications including interactions involving viral proteins
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9615(canlf-mdck)
taxid:9615("Canis familiaris (dog) kidney epithelial cells")
Parameters of the interaction-
Creation date2018/04/23
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Agaussia-n:c-c
Feature(s) for interactor Bgaussia-c:c-c
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ATag visualisation by luciferase assay
Participant identification method for interactor BTag visualisation by luciferase assay