Curation Details
Interaction ID: IM-28220-5

Unique identifier for interactor Auniprotkb:P25490
Unique identifier for interactor Buniprotkb:Q07009
Alternative identifier for interactor Aintact:EBI-765538
ensembl:ENSP00000262238.4
uniprotkb:Q14935
Alternative identifier for interactor Bintact:EBI-1040438
ensembl:ENSRNOP00000046509.3
ensembl:ENSRNOP00055017508
ensembl:ENSRNOP00060009674
ensembl:ENSRNOP00065023675
Aliases for Apsi-mi:tyy1_human(display_long)
uniprotkb:Yin and yang 1(gene name synonym)
uniprotkb:Delta transcription factor(gene name synonym)
uniprotkb:NF-E1(gene name synonym)
uniprotkb:YY1(gene name)
psi-mi:YY1(display_short)
uniprotkb:INO80S(gene name synonym)
uniprotkb:INO80 complex subunit S(gene name synonym)
Aliases for Bpsi-mi:can2_rat(display_long)
uniprotkb:Capn2(gene name)
psi-mi:Capn2(display_short)
uniprotkb:Calpain-2 large subunit(gene name synonym)
uniprotkb:Calcium-activated neutral proteinase 2(gene name synonym)
uniprotkb:Calpain M-type(gene name synonym)
uniprotkb:Millimolar-calpain(gene name synonym)
Interaction detection methodspsi-mi:"MI:0435"(protease assay)
First authorKalenik et al. (1997)
Identifier of the publicationmint:MINT-5221304
pubmed:9016636
imex:IM-28220
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:10116(rat)
taxid:10116("Rattus norvegicus (Rat)")
Interaction typespsi-mi:"MI:0570"(protein cleavage)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-25764179
imex:IM-28220-5
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f7
comment:homomint
comment:mint
comment:Figure 7 shows that incubation of YY1 with m-calpain in the presence of 1 mM CaCl2 generated a 40 kDa cleavage product. Preincubation of GST–YAF2 with YY1 dramatically enhanced the cleavage of YY1
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2002/07/21
Update date2020/07/30
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot