Curation Details
Interaction ID: IM-28216-1

Unique identifier for interactor Auniprotkb:P27986
Unique identifier for interactor Buniprotkb:P17948
Alternative identifier for interactor Aintact:EBI-79464
intact:EBI-28974553
uniprotkb:Q15747
uniprotkb:Q4VBZ7
uniprotkb:Q53EM6
uniprotkb:Q8IXA2
uniprotkb:Q8N1C5
uniprotkb:D3DWA0
uniprotkb:B3KT19
uniprotkb:E7EX19
ensembl:ENSP00000428056.1
ensembl:ENSP00000429277.1
ensembl:ENSP00000513316.1
ensembl:ENSP00000513333.1
Alternative identifier for interactor Bintact:EBI-1026718
uniprotkb:B0LPF1
uniprotkb:B3FR89
uniprotkb:B5A923
uniprotkb:O60722
uniprotkb:P16057
uniprotkb:Q12954
uniprotkb:A8KA71
uniprotkb:A3E342
uniprotkb:A3E344
uniprotkb:B2BF46
uniprotkb:B2BF47
uniprotkb:F5H5L6
ensembl:ENSP00000282397.4
uniprotkb:B2BF48
Aliases for Apsi-mi:p85a_human(display_long)
uniprotkb:PIK3R1(gene name)
psi-mi:PIK3R1(display_short)
uniprotkb:GRB1(gene name synonym)
uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym)
Aliases for Bpsi-mi:vgfr1_human(display_long)
uniprotkb:Vascular permeability factor receptor(gene name synonym)
uniprotkb:Tyrosine-protein kinase receptor FLT(gene name synonym)
uniprotkb:Tyrosine-protein kinase FRT(gene name synonym)
uniprotkb:Fms-like tyrosine kinase 1(gene name synonym)
uniprotkb:FLT1(gene name)
psi-mi:FLT1(display_short)
uniprotkb:FLT(gene name synonym)
uniprotkb:FRT(gene name synonym)
uniprotkb:VEGFR1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0018"(two hybrid)
First authorCunningham et al. (1995)
Identifier of the publicationmint:MINT-6730410
pubmed:7657594
imex:IM-28216
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-25763908
imex:IM-28216-1
Confidence scoreintact-miscore:0.52
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:table1
comment:homomint
comment:mint
curation depth:imex curation
full coverage:Only protein-protein interactions
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:559292(yeast)
taxid:559292(Saccharomyces cerevisiae)
Parameters of the interaction-
Creation date2010/09/29
Update date2024/09/12
negative Boolean valuefalse
Feature(s) for interactor Asufficient binding region:613-724
Feature(s) for interactor Bmutation disrupting interaction:1213-1213(MINT-8038012)
binding-associated region:781-1338(MINT-8038010)
mutation with no effect:1130-1130
mutation with no effect:1309-1309
mutation disrupting interaction:861-861
mutation with no effect:1327-1327
mutation with no effect:1124-1124,1184-1184,1333-1333
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant