Curation Details
Interaction ID: IM-27922-19

Unique identifier for interactor Auniprotkb:A0A3G5BIZ0
Unique identifier for interactor Buniprotkb:P52292
Alternative identifier for interactor Aintact:EBI-25564606
Alternative identifier for interactor Bintact:EBI-349938
intact:EBI-28977049
uniprotkb:B9EJD6
uniprotkb:Q53YE3
intact:EBI-9377406
uniprotkb:Q6NVW7
ensembl:ENSP00000332455.3
ensembl:ENSP00000438483.2
ensembl:ENSP00000462331.2
ensembl:ENSP00000463602.2
ensembl:ENSP00000504655.1
ensembl:ENSP00000504685.1
uniprotkb:Q9BRU5
Aliases for Apsi-mi:a0a3g5biz0_sars(display_long)
uniprotkb:Non-structural protein 6(gene name synonym)
uniprotkb:Accessory protein 6(gene name synonym)
Aliases for Bpsi-mi:ima1_human(display_long)
uniprotkb:KPNA2(gene name)
psi-mi:KPNA2(display_short)
uniprotkb:RCH1(gene name synonym)
uniprotkb:SRP1(gene name synonym)
uniprotkb:Karyopherin subunit alpha-2(gene name synonym)
uniprotkb:SRP1-alpha(gene name synonym)
uniprotkb:RAG cohort protein 1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorFrieman et al. (2007)
Identifier of the publicationimex:IM-27922
pubmed:17596301
NCBI Taxonomy identifier for interactor Ataxid:228330(SARS coronavirus Urbani)
taxid:228330(SARS coronavirus Urbani)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-25565412
imex:IM-27922-19
Confidence scoreintact-miscore:0.52
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 8
comment:"\"We further characterized the alanine mutants by determining whether KPNA2 would be retained in the ER/Golgi membrane. Under conditions in which ORF654-58Ala and ORF659-63Ala did not retain KPNA2, the ORF649-53Ala product still retained KPNA2 at the ER/Golgi membrane by confocal microscopy (Fig.8).\""
dataset:Coronavirus - Interactions investigated in the context of Coronavirus
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9534(chlae-vero)
taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells")
Parameters of the interaction-
Creation date2020/04/15
Update date2020/04/16
negative Boolean valuefalse
Feature(s) for interactor Amutation decreasing interaction rate:54-58
ha tag:?-?
mutation decreasing interaction rate:59-63
Feature(s) for interactor Bflag tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ATag visualisation
Participant identification method for interactor BTag visualisation