Curation Details
Interaction ID: IM-27922-15

Unique identifier for interactor Auniprotkb:P42224
Unique identifier for interactor Buniprotkb:P52294
Alternative identifier for interactor Aintact:EBI-1057697
uniprotkb:Q53XW4
uniprotkb:B2RCA0
uniprotkb:Q9UDL5
uniprotkb:A8K989
uniprotkb:D2KFR8
uniprotkb:Q68D00
uniprotkb:D3DPI7
ensembl:ENSP00000354394.4
ensembl:ENSP00000386244.1
ensembl:ENSP00000388240.2
ensembl:ENSP00000438703.2
ensembl:ENSP00000513582.1
uniprotkb:Q53S88
Alternative identifier for interactor Bintact:EBI-358383
uniprotkb:D3DN93
ensembl:ENSP00000343701.6
uniprotkb:Q9BQ56
uniprotkb:Q6IBQ9
intact:EBI-1058734
Aliases for Apsi-mi:stat1_human(display_long)
uniprotkb:STAT1(gene name)
psi-mi:STAT1(display_short)
uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym)
Aliases for Bpsi-mi:ima5_human(display_long)
uniprotkb:KPNA1(gene name)
psi-mi:KPNA1(display_short)
uniprotkb:RCH2(gene name synonym)
uniprotkb:Karyopherin subunit alpha-1(gene name synonym)
uniprotkb:SRP1-beta(gene name synonym)
uniprotkb:RAG cohort protein 2(gene name synonym)
uniprotkb:Nucleoprotein interactor 1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorFrieman et al. (2007)
Identifier of the publicationimex:IM-27922
pubmed:17596301
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-25565323
imex:IM-27922-15
Confidence scoreintact-miscore:0.62
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 6a lane 9-10
agonist:"\"INF-beta (UniProtKB:P01574)\""
comment:"\"As shown in Fig.3A, KPNA1 binds to STAT1 only after treatment with IFN-β (Fig.6A, lane 2). Consistent with previous findings, this interaction is independent of ORF6 expression (Fig.6A, lanes 9 and 10), since in the presence of ORF6, KPNA1 still binds STAT1 after IFN-β treatment.\""
dataset:Coronavirus - Interactions investigated in the context of Coronavirus
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2020/04/15
Update date2020/04/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bflag tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot