| Unique identifier for interactor A | uniprotkb:Q15599 |
| Unique identifier for interactor B | uniprotkb:B7UR60 |
| Alternative identifier for interactor A | intact:EBI-1149760 uniprotkb:O00272 uniprotkb:O00556 uniprotkb:Q3KQY7 uniprotkb:D3DU84 uniprotkb:D3DU85 uniprotkb:H3BSV6 ensembl:ENSP00000408005.2 intact:EBI-15579694 |
| Alternative identifier for interactor B | intact:EBI-25435618 |
| Aliases for A | psi-mi:nhrf2_human(display_long) uniprotkb:NHERF2(gene name) psi-mi:NHERF2(display_short) uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym) uniprotkb:SLC9A3R2(gene name synonym) uniprotkb:SRY-interacting protein 1(gene name synonym) uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym) uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym) uniprotkb:Tyrosine kinase activator protein 1(gene name synonym) |
| Aliases for B | psi-mi:b7ur60_eco27(display_long) uniprotkb:E2348C_1442(locus name) |
| Interaction detection methods | psi-mi:"MI:0416"(fluorescence microscopy) |
| First author | Martinez et al. (2010) |
| Identifier of the publication | pubmed:20618342 imex:IM-27748 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:574521(eco27) taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)") |
| Interaction types | psi-mi:"MI:0403"(colocalization) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-25436646 imex:IM-27748-24 |
| Confidence score | intact-miscore:0.69 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:fig. 3 suppl fig.2 comment:"\"In order to determine if the effectors colocalize with NHERF2, HeLa–NHERF2 cells were transfected with pRK5 (Fig. 3) or pRK5 expressing myc-tagged Map, MapΔC3, NleH1 and NleH1ΔC4 as well as pGFP-EspI and pGFP-EspIΔC7. Analysing the transfected cells by immunofluorescence revealed that Map colocalized with mitochondria (Fig. S1) and NHERF2 (Fig. 3). Plasma membrane-associated EspI and NleH1 colocalized with NHERF2 (Fig. 3). We observed no colocalization of NHERF2 and MapΔC3, EspIΔC7 or NleH1ΔC4 (Fig. S2).\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-hela) taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell) |
| Parameters of the interaction | - |
| Creation date | 2020/02/24 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | ha tag:?-? |
| Feature(s) for interactor B | green fluorescent protein tag:?-? |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Immunostaining |
| Participant identification method for interactor B | Immunostaining |