Curation Details
Interaction ID: IM-27561-3

Unique identifier for interactor Auniprotkb:P63000
Unique identifier for interactor Buniprotkb:P46940
Alternative identifier for interactor Aintact:EBI-413628
uniprotkb:O95501
uniprotkb:P15154
uniprotkb:Q3Y4D3
uniprotkb:Q9BTB4
uniprotkb:Q5JAA8
ensembl:ENSP00000258737.7
Alternative identifier for interactor Bintact:EBI-297509
intact:EBI-25601492
uniprotkb:A7MBM3
ensembl:ENSP00000268182.5
Aliases for Apsi-mi:rac1_human(display_long)
uniprotkb:RAC1(gene name)
psi-mi:RAC1(display_short)
uniprotkb:MIG5(orf name)
uniprotkb:p21-Rac1(gene name synonym)
uniprotkb:Ras-like protein TC25(gene name synonym)
uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)
uniprotkb:TC25(gene name synonym)
Aliases for Bpsi-mi:iqga1_human(display_long)
uniprotkb:IQGAP1(gene name)
psi-mi:IQGAP1(display_short)
uniprotkb:KIAA0051(gene name synonym)
uniprotkb:p195(gene name synonym)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorBrown et al. (2008)
Identifier of the publicationimex:IM-27561
pubmed:18809683
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-22275455
imex:IM-27561-3
Confidence scoreintact-miscore:0.92
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 2
comment:"\"HeLa cells were fixed before and after infection with GFP EPEC (3 h) and stained for IQGAP1 (blue) and either Rac1 or Cdc42 (red) (Fig. 2). As described previously (20, 22), IQGAP1 colocalizes with both Rac1 and Cdc42 around the periphery of noninfected cells (Fig. 2). Neither Rac1 nor Cdc42 localizes at sites of EPEC adhesion (Fig. 2).\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hela)
taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2019/12/10
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AImmunostaining
Participant identification method for interactor BImmunostaining