Curation Details
Interaction ID: IM-27552-6

Unique identifier for interactor Auniprotkb:Q8X482
Unique identifier for interactor Buniprotkb:Q14247
Alternative identifier for interactor Aintact:EBI-22229752
Alternative identifier for interactor Bintact:EBI-351886
ensembl:ENSP00000301843.8
ensembl:ENSP00000500756.1
uniprotkb:Q8N707
uniprotkb:Q96H99
intact:EBI-3959948
Aliases for Apsi-mi:espfu_eco57(display_long)
uniprotkb:EspF-like protein encoded on prophage U(gene name synonym)
uniprotkb:Tir-cytoskeleton coupling protein TccP(gene name synonym)
uniprotkb:"espF(U)"(gene name)
psi-mi:"espF(U)"(display_short)
uniprotkb:tccP(gene name synonym)
uniprotkb:Z3072(locus name)
Aliases for Bpsi-mi:src8_human(display_long)
uniprotkb:CTTN(gene name)
psi-mi:CTTN(display_short)
uniprotkb:EMS1(gene name synonym)
uniprotkb:Amplaxin(gene name synonym)
uniprotkb:Oncogene EMS1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorCantarelli et al. (2007)
Identifier of the publicationimex:IM-27552
pubmed:17451412
NCBI Taxonomy identifier for interactor Ataxid:83334(eco57)
taxid:83334("Escherichia coli O157:H7")
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-22272907
imex:IM-27552-6
Confidence scoreintact-miscore:0.27
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 4c
comment:"\"Infection of HeLa cells with DMEM‐activated EHEC expressing FLAG‐tagged EspFu (as in Fig. 2C and D) resulted in a perfect colocalization of EspFu‐FLAG and tyrosine‐phosphorylated cortactin, which was visible 45 min after infection (Fig. 4C). As the infection proceeded (120 min), cortactin was dephosphorylated and only EspFu‐FLAG was detected near the bacteria.\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hela)
taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2019/12/02
Update date2019/12/05
negative Boolean valuefalse
Feature(s) for interactor Aflag tag:?-?
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag immunostaining
Participant identification method for interactor BImmunostaining