Curation Details
Interaction ID: IM-27538-7

Unique identifier for interactor Auniprotkb:B7UM99
Unique identifier for interactor Buniprotkb:P27348
Alternative identifier for interactor Aintact:EBI-2504426
uniprotkb:O50190
uniprotkb:O52147
Alternative identifier for interactor Bintact:EBI-359854
uniprotkb:D6W4Z5
uniprotkb:Q567U5
uniprotkb:Q5TZU8
uniprotkb:Q9UP48
ensembl:ENSP00000238081.3
ensembl:ENSP00000371267.4
Aliases for Apsi-mi:tir_eco27(display_long)
uniprotkb:tir(gene name)
psi-mi:tir(display_short)
uniprotkb:Secreted effector protein Tir(gene name synonym)
uniprotkb:espE(gene name synonym)
uniprotkb:E2348C_3941(locus name)
Aliases for Bpsi-mi:1433t_human(display_long)
uniprotkb:YWHAQ(gene name)
psi-mi:YWHAQ(display_short)
uniprotkb:14-3-3 protein tau(gene name synonym)
uniprotkb:14-3-3 protein T-cell(gene name synonym)
uniprotkb:Protein HS1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0018"(two hybrid)
First authorPatel et al. (2006)
Identifier of the publicationimex:IM-27538
pubmed:16367866
NCBI Taxonomy identifier for interactor Ataxid:574521(eco27)
taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-22235221
imex:IM-27538-7
Confidence scoreintact-miscore:0.66
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:table 1 fig. 1
comment:"\"None of these Tir subfragments showed β‐galactosidase activities above that of the host or single plasmid‐bearing control strains (Fig. 1B). In yeast, the complete Tir molecule is required for recognition by 14‐3‐3τ.\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:559292(yeast)
taxid:559292(Saccharomyces cerevisiae)
Parameters of the interaction-
Creation date2019/11/27
Update date2019/12/02
negative Boolean valuefalse
Feature(s) for interactor Amutation with no effect:51-51
mutation with no effect:434-434
mutation with no effect:465-465
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant