Curation Details
Interaction ID: IM-27538-17

Unique identifier for interactor Auniprotkb:P27348
Unique identifier for interactor Buniprotkb:B7UM99
Alternative identifier for interactor Aintact:EBI-359854
uniprotkb:D6W4Z5
uniprotkb:Q567U5
uniprotkb:Q5TZU8
uniprotkb:Q9UP48
ensembl:ENSP00000238081.3
ensembl:ENSP00000371267.4
Alternative identifier for interactor Bintact:EBI-2504426
uniprotkb:O50190
uniprotkb:O52147
Aliases for Apsi-mi:1433t_human(display_long)
uniprotkb:YWHAQ(gene name)
psi-mi:YWHAQ(display_short)
uniprotkb:14-3-3 protein tau(gene name synonym)
uniprotkb:14-3-3 protein T-cell(gene name synonym)
uniprotkb:Protein HS1(gene name synonym)
Aliases for Bpsi-mi:tir_eco27(display_long)
uniprotkb:tir(gene name)
psi-mi:tir(display_short)
uniprotkb:Secreted effector protein Tir(gene name synonym)
uniprotkb:espE(gene name synonym)
uniprotkb:E2348C_3941(locus name)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorPatel et al. (2006)
Identifier of the publicationimex:IM-27538
pubmed:16367866
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:574521(eco27)
taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-22235436
imex:IM-27538-17
Confidence scoreintact-miscore:0.66
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 4
comment:14‐3‐3τ was found throughout the host cell but was observed to accumulate adjacent to Tir localized at the extremity of the actin‐stained pedestal. The tips of the pedestals represent the interface of the bacterial attachment site and the location of Tir as it interacts with intimin
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hela)
taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2019/11/27
Update date2019/12/02
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AImmunostaining
Participant identification method for interactor BImmunostaining