Curation Details
Interaction ID: IM-27538-13

Unique identifier for interactor Auniprotkb:B7UM99
Unique identifier for interactor Buniprotkb:P27348
Alternative identifier for interactor Aintact:EBI-2504426
uniprotkb:O50190
uniprotkb:O52147
Alternative identifier for interactor Bintact:EBI-359854
uniprotkb:Q567U5
uniprotkb:Q5TZU8
uniprotkb:Q9UP48
ensembl:ENSP00000238081.3
ensembl:ENSP00000371267.4
uniprotkb:D6W4Z5
Aliases for Apsi-mi:tir_eco27(display_long)
uniprotkb:tir(gene name)
psi-mi:tir(display_short)
uniprotkb:Secreted effector protein Tir(gene name synonym)
uniprotkb:espE(gene name synonym)
uniprotkb:E2348C_3941(locus name)
Aliases for Bpsi-mi:1433t_human(display_long)
uniprotkb:YWHAQ(gene name)
psi-mi:YWHAQ(display_short)
uniprotkb:14-3-3 protein tau(gene name synonym)
uniprotkb:14-3-3 protein T-cell(gene name synonym)
uniprotkb:Protein HS1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorPatel et al. (2006)
Identifier of the publicationimex:IM-27538
pubmed:16367866
NCBI Taxonomy identifier for interactor Ataxid:574521(eco27)
taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-22235416
imex:IM-27538-13
Confidence scoreintact-miscore:0.66
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig 3
comment:The 14‐3‐3τ and cytokeratin 18 proteins were observed to co‐precipitate with Tir in the wild‐type EPEC‐infected membrane and cytoplasmic extracts but were absent in the ΔTir control.
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hela)
taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2019/11/27
Update date2024/08/11
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot