Curation Details
Interaction ID: IM-27522-7

Unique identifier for interactor Auniprotkb:B7UM99
Unique identifier for interactor Buniprotkb:O00401
Alternative identifier for interactor Aintact:EBI-2504426
uniprotkb:O50190
uniprotkb:O52147
Alternative identifier for interactor Bintact:EBI-957615
uniprotkb:A1JUI9
ensembl:ENSP00000223023.4
uniprotkb:Q7Z746
Aliases for Apsi-mi:tir_eco27(display_long)
uniprotkb:tir(gene name)
psi-mi:tir(display_short)
uniprotkb:Secreted effector protein Tir(gene name synonym)
uniprotkb:espE(gene name synonym)
uniprotkb:E2348C_3941(locus name)
Aliases for Bpsi-mi:wasl_human(display_long)
uniprotkb:WASL(gene name)
psi-mi:WASL(display_short)
uniprotkb:Neural Wiskott-Aldrich syndrome protein(gene name synonym)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorCampellone et al. (2004)
Identifier of the publicationimex:IM-27522
pubmed:15296718
NCBI Taxonomy identifier for interactor Ataxid:574521(eco27)
taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-22229787
imex:IM-27522-7
Confidence scoreintact-miscore:0.27
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 5b
comment:"\"Fluorescent antibody staining of HeLa cells infected with KC12 expressing EspFU demonstrated that HA-tagged EHEC Tir and myc-tagged EspFU precisely colocalized beneath adherent bacteria (Figure 5B), suggesting that they may physically associate during pedestal formation.\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hela)
taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2019/11/27
Update date2019/11/27
negative Boolean valuefalse
Feature(s) for interactor Aha tag:?-?
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AImmunostaining
Participant identification method for interactor BImmunostaining