Curation Details
Interaction ID: IM-27518-13

Unique identifier for interactor Auniprotkb:P05787
Unique identifier for interactor Buniprotkb:B7UM99
Alternative identifier for interactor Aintact:EBI-297852
uniprotkb:Q14099
uniprotkb:Q14716
uniprotkb:Q14717
uniprotkb:Q53GJ0
uniprotkb:Q6DHW5
uniprotkb:Q6GMY0
uniprotkb:Q6P4C7
uniprotkb:Q96J60
uniprotkb:A8K4H3
uniprotkb:B0AZN5
uniprotkb:F8VXB4
ensembl:ENSP00000293308.6
ensembl:ENSP00000447402.1
ensembl:ENSP00000447566.1
ensembl:ENSP00000509398.1
Alternative identifier for interactor Bintact:EBI-2504426
uniprotkb:O50190
uniprotkb:O52147
Aliases for Apsi-mi:k2c8_human(display_long)
uniprotkb:Keratin-8(gene name synonym)
uniprotkb:KRT8(gene name)
psi-mi:KRT8(display_short)
uniprotkb:CYK8(gene name synonym)
uniprotkb:Cytokeratin-8(gene name synonym)
uniprotkb:Type-II keratin Kb8(gene name synonym)
Aliases for Bpsi-mi:tir_eco27(display_long)
uniprotkb:tir(gene name)
psi-mi:tir(display_short)
uniprotkb:Secreted effector protein Tir(gene name synonym)
uniprotkb:espE(gene name synonym)
uniprotkb:E2348C_3941(locus name)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorBatchelor et al. (2004)
Identifier of the publicationimex:IM-27518
pubmed:14710194
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:574521(eco27)
taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-22229135
imex:IM-27518-13
Confidence scoreintact-miscore:0.46
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 3
comment:Colocalization of Tir and CK18 in EPEC‐induced pedestals was also observed in the human intestinal epithelial INT407 and Caco‐2 cell lines.
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hela)
taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2019/11/25
Update date2024/07/17
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AImmunostaining
Participant identification method for interactor BImmunostaining