Curation Details
Interaction ID: IM-27518-11

Unique identifier for interactor Auniprotkb:P05783
Unique identifier for interactor Buniprotkb:B7UM99
Alternative identifier for interactor Aintact:EBI-297888
uniprotkb:Q53G38
uniprotkb:Q5U0N8
uniprotkb:Q9BW26
ensembl:ENSP00000373487.3
ensembl:ENSP00000373489.2
Alternative identifier for interactor Bintact:EBI-2504426
uniprotkb:O50190
uniprotkb:O52147
Aliases for Apsi-mi:k1c18_human(display_long)
uniprotkb:KRT18(gene name)
psi-mi:KRT18(display_short)
uniprotkb:CYK18(gene name synonym)
uniprotkb:Keratin-18(gene name synonym)
uniprotkb:PIG46(orf name)
uniprotkb:Cytokeratin-18(gene name synonym)
uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)
Aliases for Bpsi-mi:tir_eco27(display_long)
uniprotkb:tir(gene name)
psi-mi:tir(display_short)
uniprotkb:Secreted effector protein Tir(gene name synonym)
uniprotkb:espE(gene name synonym)
uniprotkb:E2348C_3941(locus name)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorBatchelor et al. (2004)
Identifier of the publicationimex:IM-27518
pubmed:14710194
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:574521(eco27)
taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-22229127
imex:IM-27518-11
Confidence scoreintact-miscore:0.66
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 3,4
comment:Colocalization of Tir and CK18 in EPEC‐induced pedestals was also observed in the human intestinal epithelial INT407 and Caco‐2 cell lines.
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hela)
taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2019/11/25
Update date2024/06/04
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AImmunostaining
Participant identification method for interactor BImmunostaining