| Unique identifier for interactor A | uniprotkb:Q02156 |
| Unique identifier for interactor B | uniprotkb:P15056 |
| Alternative identifier for interactor A | intact:EBI-706254 uniprotkb:Q32MQ3 uniprotkb:Q53SL4 uniprotkb:Q53SM5 uniprotkb:Q9UE81 uniprotkb:B0LPH7 ensembl:ENSP00000306124.3 |
| Alternative identifier for interactor B | intact:EBI-365980 uniprotkb:Q13878 uniprotkb:Q3MIN6 intact:EBI-28988924 uniprotkb:Q9UDP8 uniprotkb:Q9Y6T3 uniprotkb:A4D1T4 uniprotkb:B6HY61 uniprotkb:B6HY62 uniprotkb:B6HY63 uniprotkb:B6HY64 uniprotkb:B6HY65 uniprotkb:B6HY66 ensembl:ENSP00000493543.1 |
| Aliases for A | psi-mi:kpce_human(display_long) uniprotkb:nPKC-epsilon(gene name synonym) uniprotkb:PRKCE(gene name) psi-mi:PRKCE(display_short) uniprotkb:PKCE(gene name synonym) |
| Aliases for B | psi-mi:braf_human(display_long) uniprotkb:BRAF(gene name) psi-mi:BRAF(display_short) uniprotkb:BRAF1(gene name synonym) uniprotkb:RAFB1(gene name synonym) uniprotkb:v-Raf murine sarcoma viral oncogene homolog B1(gene name synonym) uniprotkb:p94(gene name synonym) uniprotkb:Proto-oncogene B-Raf(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0006"(anti bait coimmunoprecipitation) |
| First author | Carmo et al. (2010) |
| Identifier of the publication | pubmed:21625473 imex:IM-27434 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-22091416 imex:IM-27434-3 |
| Confidence score | intact-miscore:0.59 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:fig. 2b comment:"\"To substantiate the notion that the three proteins interacted, we next immunoprecipitated either PKCĪµ (Fig. 2B) or B-RAF (Fig. 2C) from cell lysates. We then performed western blotting to probe for these proteins and S6K2. While B-RAF and PKCĪµ basal interaction increased 10 min after FGF-2 stimulation and subsequently persisted, we were unable to detect S6K2 in these immunoprecipitates (Fig. 2B, 2C and data not shown).\"" variable_condition:FGF2 treatment increases interaction at 10' curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-u2os) taxid:9606(Homo sapiens U2OS osteosarcoma cell) |
| Parameters of the interaction | - |
| Creation date | 2019/10/14 |
| Update date | 2024/11/18 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |