| Unique identifier for interactor A | uniprotkb:P16725 |
| Unique identifier for interactor B | uniprotkb:Q04206 |
| Alternative identifier for interactor A | intact:EBI-22086047 uniprotkb:Q7M6L6 |
| Alternative identifier for interactor B | intact:EBI-73886 uniprotkb:Q6GTV1 uniprotkb:Q6SLK1 ensembl:ENSP00000384273.3 |
| Aliases for A | psi-mi:ul76_hcmva(display_long) uniprotkb:UL76(gene name) psi-mi:UL76(display_short) |
| Aliases for B | psi-mi:tf65_human(display_long) uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym) uniprotkb:RELA(gene name) psi-mi:RELA(display_short) uniprotkb:NFKB3(gene name synonym) uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0416"(fluorescence microscopy) |
| First author | Costa et al. (2013) |
| Identifier of the publication | pubmed:24068928 imex:IM-27431 |
| NCBI Taxonomy identifier for interactor A | taxid:10360(hcmva) taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0403"(colocalization) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-22086045 imex:IM-27431-1 |
| Confidence score | intact-miscore:0.27 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:fig. 3b comment:After IkBα degradation by the proteosome, dimers of NF-kB subunits translocate to the nucleus where they bind to the target gene promoter region and activate transcription [9]. Thus, we evaluated the effects of UL76 expression on the subcellular localization of the NF-kB p65 subunit by immunofluorescence. As shown in Figure 3B, p65 was localized in the nucleus of the UL76-transfected HFF cells, in contrast to its cytoplasmic localization in control cells. curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-fibroblast) taxid:9606(Homo sapiens diploid fibroblast) |
| Parameters of the interaction | - |
| Creation date | 2019/10/14 |
| Update date | 2024/11/06 |
| negative Boolean value | false |
| Feature(s) for interactor A | ha tag:?-? |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Tag visualisation by fluorescence |
| Participant identification method for interactor B | Tag visualisation by fluorescence |