| Unique identifier for interactor A | uniprotkb:Q2HR75 |
| Unique identifier for interactor B | uniprotkb:Q96QD9 |
| Alternative identifier for interactor A | intact:EBI-6884751 uniprotkb:O40938 |
| Alternative identifier for interactor B | intact:EBI-724553 uniprotkb:Q96SL9 uniprotkb:Q9BQI8 uniprotkb:A8MY74 uniprotkb:B2RCB2 uniprotkb:B7Z3R4 uniprotkb:B7Z7V1 uniprotkb:B7Z8I0 uniprotkb:B7ZAJ3 uniprotkb:C9J7P6 uniprotkb:C9JNG6 uniprotkb:C9JTH3 uniprotkb:C9JY50 ensembl:ENSP00000241502.3 |
| Aliases for A | psi-mi:mta_hhv8p(display_long) uniprotkb:EB2 protein homolog(gene name synonym) uniprotkb:ORF57(orf name) |
| Aliases for B | psi-mi:uif_human(display_long) uniprotkb:UIF(gene name synonym) uniprotkb:FYTTD1(gene name) psi-mi:FYTTD1(display_short) uniprotkb:Forty-two-three domain-containing protein 1(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0006"(anti bait coimmunoprecipitation) |
| First author | Jackson et al. (2011) |
| Identifier of the publication | pubmed:21814512 imex:IM-27426 |
| NCBI Taxonomy identifier for interactor A | taxid:868565(hhv8p) taxid:868565(Human herpesvirus 8) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-22084573 imex:IM-27426-11 |
| Confidence score | intact-miscore:0.65 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:fig. 2 comment:"\"In order to address potential overexpression artefacts of the above co-immunoprecipitation experiments and also determine whether ORF57 interacts with UIF during KSHV lytic replication, latently-infected BCBL-1 cells remained uninduced or reactivated using the phorbol ester, TPA. Lytic expression was confirmed by the detection of ORF57 using Western blot analysis in the reactivated samples (Figure 2). Uninduced and reactivated cell lysates were then incubated with no antibody control, ORF57- or UIF-specific antibodies. Reciprocal western blot analysis using the antibodies in reverse demonstrated that ORF57 interacts with UIF during KSHV lytic replication (Figure 2). Therefore, these data provide the first evidence of a viral protein associating with UIF.\"" variable_condition:TPA treatment curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-bcbl_1) taxid:9606(Homo sapiens BCBL-1 B-cell lymphoma cell) |
| Parameters of the interaction | - |
| Creation date | 2019/10/09 |
| Update date | 2025/01/15 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |