Unique identifier for interactor A | uniprotkb:Q14643 |
Unique identifier for interactor B | uniprotkb:O43561 |
Alternative identifier for interactor A | intact:EBI-465548 uniprotkb:Q14660 uniprotkb:Q99897 ensembl:ENSP00000497605.1 uniprotkb:E7EPX7 uniprotkb:E9PDE9 |
Alternative identifier for interactor B | intact:EBI-1222766 uniprotkb:O43919 uniprotkb:B7WPI0 uniprotkb:C7C5T6 uniprotkb:G5E9K3 ensembl:ENSP00000354119.5 |
Aliases for A | psi-mi:itpr1_human(display_long) uniprotkb:ITPR1(gene name) psi-mi:ITPR1(display_short) uniprotkb:INSP3R1(gene name synonym) uniprotkb:Type 1 inositol 1,4,5-trisphosphate receptor(gene name synonym) uniprotkb:IP3 receptor isoform 1(gene name synonym) uniprotkb:Inositol 1,4,5 trisphosphate receptor(gene name synonym) uniprotkb:Inositol 1,4,5-trisphosphate receptor type 1(gene name synonym) |
Aliases for B | psi-mi:lat_human(display_long) uniprotkb:36 kDa phosphotyrosine adapter protein(gene name synonym) uniprotkb:LAT(gene name) psi-mi:LAT(display_short) uniprotkb:p36-38(gene name synonym) |
Interaction detection methods | psi-mi:"MI:0006"(anti bait coimmunoprecipitation) |
First author | deSouza et al. (2007) |
Identifier of the publication | imex:IM-27419 pubmed:18056410 |
NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
Interaction types | psi-mi:"MI:0915"(physical association) |
Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
Interaction identifier(s) in the corresponding source database | intact:EBI-22080929 imex:IM-27419-1 |
Confidence score | intact-miscore:0.40 |
Complex expansion | - |
Biological role A | Unspecified role |
Biological role B | Unspecified role |
Experimental role A | Bait |
Experimental role B | Prey |
Interactor type A | Protein |
Interactor type B | Protein |
Annotations for the interaction | figure legend:fig.1b comment:"\"In ZAP-70-deficient T cells, LAT did not coimmunoprecipitate with IP3R1 (Fig. 1 B), which suggests that the association of IP3R1 with LAT is mediated by phosphorylation of LAT by ZAP-70.\"" agonist:"\"ZAP-70 (UniProtKB:P43403)\"" curation depth:imex curation full coverage:Only protein-protein interactions |
NCBI Taxonomy identifier for the host organism | taxid:9606(human-jurkat) taxid:9606(Homo sapiens Jurkat T-cell leukemia cell) |
Parameters of the interaction | - |
Creation date | 2019/10/08 |
Update date | 2024/11/14 |
negative Boolean value | false |
Feature(s) for interactor A | - |
Feature(s) for interactor B | - |
Stoichiometry for interactor A | - |
Stoichiometry for interactor B | - |
Participant identification method for interactor A | Western blot |
Participant identification method for interactor B | Western blot |