| Unique identifier for interactor A | uniprotkb:Q12772 |
| Unique identifier for interactor B | intact:EBI-9837510 |
| Alternative identifier for interactor A | intact:EBI-465059 ensembl:ENSP00000354476.4 uniprotkb:Q86V36 uniprotkb:Q6GTH7 uniprotkb:Q9UH04 uniprotkb:Q05BD5 |
| Alternative identifier for interactor B | - |
| Aliases for A | psi-mi:srbp2_human(display_long) uniprotkb:SREBF2(gene name) psi-mi:SREBF2(display_short) uniprotkb:SREBP2(gene name synonym) uniprotkb:Sterol regulatory element-binding transcription factor 2(gene name synonym) uniprotkb:BHLHD2(gene name synonym) uniprotkb:Class D basic helix-loop-helix protein 2(gene name synonym) |
| Aliases for B | psi-mi:ldlr_human_sre_dna-probe(display_short) psi-mi:EBI-9837510(display_long) |
| Interaction detection methods | psi-mi:"MI:0413"(electrophoretic mobility shift assay) |
| First author | Misawa et al. (2003) |
| Identifier of the publication | pubmed:12855700 mint:MINT-5216527 imex:IM-27301 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-9837535 imex:IM-27301-7 |
| Confidence score | intact-miscore:0.44 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Deoxyribonucleic acid |
| Annotations for the interaction | figure legend:Fig. 5 comment:"\"Competition assays were performed by adding unlabeled SRE DNA probes from the human Sterol Isomerase gene promoter (ENSG00000147155). Excess amount of SREc probe outcompeted the LDLR SRE probe, while the SREa and SREd probes had only little effect.\"" causality statement:Q12772 increases expression at protein level of ENSG00000130164 causality statement:Q12772 and P41235 increases expression at protein level of ENSG00000130164 full coverage:Only protein-protein interactions dataset:IBD - Inflammatory bowel disease dataset:Ulcerative colitis - Interactions of proteins identified as having a link to ulcerative colitis curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2003/09/29 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | sufficient binding region:1-481 his tag:?-? |
| Feature(s) for interactor B | 32p radiolabel:?-? |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Autoradiography |
| Participant identification method for interactor B | Autoradiography |