Curation Details
Interaction ID: IM-26819-17

Unique identifier for interactor Auniprotkb:O15037
Unique identifier for interactor Buniprotkb:Q13617
Alternative identifier for interactor Aintact:EBI-6148525
uniprotkb:Q86TZ6
uniprotkb:Q8IUQ2
uniprotkb:Q96BA9
ensembl:ENSP00000251343.5
ensembl:ENSP00000450799.1
ensembl:ENSP00000451106.1
Alternative identifier for interactor Bintact:EBI-456179
ensembl:ENSP00000363880.1
ensembl:ENSP00000363881.3
ensembl:ENSP00000363883.3
ensembl:ENSP00000501215.1
ensembl:ENSP00000508908.1
ensembl:ENSP00000510691.1
uniprotkb:O00200
uniprotkb:Q5T2B6
uniprotkb:Q9UNF9
uniprotkb:D3DRY6
uniprotkb:B3KT95
uniprotkb:B7Z6K8
uniprotkb:G3V1S2
Aliases for Apsi-mi:khnyn_human(display_long)
uniprotkb:KHNYN(gene name)
psi-mi:KHNYN(display_short)
uniprotkb:KH and NYN domain-containing protein(gene name synonym)
uniprotkb:KIAA0323(gene name synonym)
Aliases for Bpsi-mi:cul2_human(display_long)
uniprotkb:CUL2(gene name)
psi-mi:CUL2(display_short)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorCastagnoli et al. (2019)
Identifier of the publicationpubmed:30659753
imex:IM-26819
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-21221469
imex:IM-26819-17
Confidence scoreintact-miscore:0.35
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig 6e
antagonist:MLN4924 inhibitor of NEDD8 activation
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2019/02/19
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Aglutathione s tranferase tag:?-?
binding-associated region:598-678
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot