| Unique identifier for interactor A | uniprotkb:O15037 |
| Unique identifier for interactor B | uniprotkb:Q15843 |
| Alternative identifier for interactor A | intact:EBI-6148525 uniprotkb:Q86TZ6 uniprotkb:Q8IUQ2 uniprotkb:Q96BA9 ensembl:ENSP00000251343.5 ensembl:ENSP00000450799.1 ensembl:ENSP00000451106.1 |
| Alternative identifier for interactor B | intact:EBI-716247 uniprotkb:Q3SXN8 uniprotkb:Q6LES6 ensembl:ENSP00000250495.5 ensembl:ENSP00000496420.1 |
| Aliases for A | psi-mi:khnyn_human(display_long) uniprotkb:KHNYN(gene name) psi-mi:KHNYN(display_short) uniprotkb:KH and NYN domain-containing protein(gene name synonym) uniprotkb:KIAA0323(gene name synonym) |
| Aliases for B | psi-mi:nedd8_human(display_long) uniprotkb:Ubiquitin-like protein Nedd8(gene name synonym) uniprotkb:Neddylin(gene name synonym) uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 8(gene name synonym) uniprotkb:NEDD8(gene name) psi-mi:NEDD8(display_short) |
| Interaction detection methods | psi-mi:"MI:0096"(pull down) |
| First author | Castagnoli et al. (2019) |
| Identifier of the publication | pubmed:30659753 imex:IM-26819 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0914"(association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-21221450 imex:IM-26819-15 |
| Confidence score | intact-miscore:0.70 |
| Complex expansion | psi-mi:"MI:1060"(spoke expansion) |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:fig 6c comment:"\"As shown in Fig. 6C, several neddylated substrates were affinity purified by the GST fusion of the KHNYN ubiquitin‐binding domain, among them CUL1 and CUL2, both of which bound to KHNYN in their neddylated forms. Conversely, no significant association was observed with the other constructs. Similar results were obtained for CUL3 and CUL4 (data not shown).\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2019/02/19 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | sufficient binding region:598-678 glutathione s tranferase tag:?-? |
| Feature(s) for interactor B | flag tag:?-? |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |