| Unique identifier for interactor A | uniprotkb:Q86YC2 |
| Unique identifier for interactor B | uniprotkb:P38398 |
| Alternative identifier for interactor A | intact:EBI-1222653 uniprotkb:Q8N7Y6 uniprotkb:Q8ND31 uniprotkb:Q9H6W1 ensembl:ENSP00000261584.4 uniprotkb:A6NIE1 |
| Alternative identifier for interactor B | intact:EBI-349905 uniprotkb:Q3LRJ6 uniprotkb:Q6IN79 uniprotkb:Q1RMC1 uniprotkb:E9PFZ0 ensembl:ENSP00000350283.3 ensembl:ENSP00000419103.2 ensembl:ENSP00000419274.2 ensembl:ENSP00000478114.2 uniprotkb:Q3LRJ0 uniprotkb:O15129 uniprotkb:Q7KYU9 |
| Aliases for A | psi-mi:palb2_human(display_long) uniprotkb:PALB2(gene name) psi-mi:PALB2(display_short) uniprotkb:FANCN(gene name synonym) |
| Aliases for B | psi-mi:brca1_human(display_long) uniprotkb:BRCA1(gene name) psi-mi:BRCA1(display_short) uniprotkb:RNF53(gene name synonym) uniprotkb:RING finger protein 53(gene name synonym) uniprotkb:RING-type E3 ubiquitin transferase BRCA1(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
| First author | Foo et al. (2017) |
| Identifier of the publication | pubmed:28319063 imex:IM-26811 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0914"(association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-21195816 imex:IM-26811-1 |
| Confidence score | intact-miscore:0.91 |
| Complex expansion | psi-mi:"MI:1060"(spoke expansion) |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:fig 2c comment:"\"Y28C and L35P both abrogated the co-IP of the endogenous BRCA1 with the ectopically expressed PALB2 proteins in 293T cells, whereas K18R, K30N and R37H did not significantly affect the complex formation (Figure 2c and data not shown). Interactions of the PALB2 variants with BRCA2 and RAD51 were all unaffected, consistent with the fact that BRCA2 binds to the C terminus of PALB2.8\"" full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-293t) taxid:9606(Homo sapiens HEK293T embryonic kidney cell) |
| Parameters of the interaction | - |
| Creation date | 2019/02/07 |
| Update date | 2022/03/24 |
| negative Boolean value | false |
| Feature(s) for interactor A | tandem tag:c-c |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |