Curation Details
Interaction ID: IM-26788-9

Unique identifier for interactor Aensembl:ENSG00000164692
Unique identifier for interactor Buniprotkb:P08047
Alternative identifier for interactor Aintact:EBI-9095879
Alternative identifier for interactor Bintact:EBI-298336
uniprotkb:Q86TN8
uniprotkb:Q9H3Q5
uniprotkb:Q9NR51
uniprotkb:Q9NY21
uniprotkb:Q9NYE7
intact:EBI-28977878
ensembl:ENSP00000329357.4
uniprotkb:E4Z9M7
uniprotkb:G5E9M8
Aliases for Apsi-mi:co1a2_human_gene(display_short)
psi-mi:ENSG00000164692(display_long)
Aliases for Bpsi-mi:sp1_human(display_long)
uniprotkb:SP1(gene name)
psi-mi:SP1(display_short)
uniprotkb:TSFP1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0402"(chromatin immunoprecipitation assay)
First authorGoffin et al. (2009)
Identifier of the publicationpubmed:20429888
imex:IM-26788
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-20620788
imex:IM-26788-9
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AGene
Interactor type BProtein
Annotations for the interactionfigure legend:f6b
comment:"\"Of note, under the same culture conditions, TGF-beta-induced binding of SP1 to the promoter region of COL1A2 was abrogated by bortezomib (Figure (Figure6b).6b).\""
antagonist:"\"bortezomib (CHEBI:52717)\""
antagonist:"\"TGFB (Species unknown)\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-fibroblast)
taxid:9606(Homo sapiens diploid fibroblast)
Parameters of the interaction-
Creation date2018/07/10
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Asufficient binding region:?-?
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AReverse transcription pcr
Participant identification method for interactor BReverse transcription pcr