| Unique identifier for interactor A | ensembl:ENSG00000196611 |
| Unique identifier for interactor B | uniprotkb:P05412 |
| Alternative identifier for interactor A | intact:EBI-10041487 |
| Alternative identifier for interactor B | intact:EBI-852823 uniprotkb:Q96G93 uniprotkb:Q6FHM7 ensembl:ENSP00000360266.2 ensembl:ENSP00000503132.1 |
| Aliases for A | psi-mi:mmp1_human_gene(display_short) psi-mi:ENSG00000196611(display_long) |
| Aliases for B | psi-mi:jun_human(display_long) uniprotkb:Transcription factor AP-1 subunit Jun(gene name synonym) uniprotkb:JUN(gene name) psi-mi:JUN(display_short) uniprotkb:Activator protein 1(gene name synonym) uniprotkb:Proto-oncogene c-Jun(gene name synonym) uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym) uniprotkb:p39(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0096"(pull down) |
| First author | Goffin et al. (2009) |
| Identifier of the publication | pubmed:20429888 imex:IM-26788 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-20620779 imex:IM-26788-7 |
| Confidence score | intact-miscore:0.69 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Gene |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f5e comment:"\"Finally, DNA pull-down experiments revealed a marked increase in the amount of c-Jun bound to the biotinylated MMP-1 probe upon bortezomib treatment (Figure (Figure5e).5e). Taken together, these experiments demonstrate that PI results in a specific increase in binding of c-Jun to the most proximal AP-1 site of the MMP-1 promoter.\"" agonist:"\"bortezomib (CHEBI:52717)\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2018/07/10 |
| Update date | 2024/06/06 |
| negative Boolean value | false |
| Feature(s) for interactor A | biotin tag:?-? |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |