| Unique identifier for interactor A | ensembl:ENSG00000164692 |
| Unique identifier for interactor B | uniprotkb:Q15796 |
| Alternative identifier for interactor A | intact:EBI-9095879 |
| Alternative identifier for interactor B | intact:EBI-1040141 ensembl:ENSP00000262160.6 ensembl:ENSP00000384449.1 |
| Aliases for A | psi-mi:co1a2_human_gene(display_short) psi-mi:ENSG00000164692(display_long) |
| Aliases for B | psi-mi:smad2_human(display_long) uniprotkb:SMAD2(gene name) psi-mi:SMAD2(display_short) uniprotkb:MADH2(gene name synonym) uniprotkb:MADR2(gene name synonym) uniprotkb:Mad-related protein 2(gene name synonym) uniprotkb:SMAD family member 2(gene name synonym) uniprotkb:JV18-1(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0096"(pull down) |
| First author | Goffin et al. (2009) |
| Identifier of the publication | pubmed:20429888 imex:IM-26788 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-20620541 imex:IM-26788-1 |
| Confidence score | intact-miscore:0.40 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Gene |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f3c comment:Using a synthetic biotinylated probe in a pull-down assay, the authors quantified binding of phospho-Smad2 to the SP1 sequence of the COL1A2 promoter. In these experiments, TGF-beta induced a substantial increase in binding of phospho-Smad2. The simultaneous presence of bortezomib did not reduce but instead enhanced binding of phospho-Smad2 in response to TGF-beta, while bortezomib on its own did not induce any binding. agonist:"\"TGFB (Species unknown)\"" agonist:"\"TGFB (Species unknown) + bortezomib (CHEBI:52717)\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2018/07/10 |
| Update date | 2024/11/22 |
| negative Boolean value | false |
| Feature(s) for interactor A | biotin tag:?-? |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |