Curation Details
Interaction ID: IM-26779-9

Unique identifier for interactor Auniprotkb:Q01094
Unique identifier for interactor Buniprotkb:Q96IZ0
Alternative identifier for interactor Aintact:EBI-448924
ensembl:ENSP00000345571.5
uniprotkb:Q13143
uniprotkb:Q92768
Alternative identifier for interactor Bintact:EBI-595869
intact:EBI-2561293
ensembl:ENSP00000328088.4
uniprotkb:O75796
uniprotkb:Q6FHY9
uniprotkb:Q8N700
Aliases for Apsi-mi:e2f1_human(display_long)
uniprotkb:Retinoblastoma-associated protein 1(gene name synonym)
uniprotkb:Retinoblastoma-binding protein 3(gene name synonym)
uniprotkb:PBR3(gene name synonym)
uniprotkb:E2F1(gene name)
psi-mi:E2F1(display_short)
uniprotkb:RBBP3(gene name synonym)
uniprotkb:pRB-binding protein E2F-1(gene name synonym)
Aliases for Bpsi-mi:pawr_human(display_long)
uniprotkb:Prostate apoptosis response 4 protein(gene name synonym)
uniprotkb:PAWR(gene name)
psi-mi:PAWR(display_short)
uniprotkb:PAR4(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorLu et al. (2008)
Identifier of the publicationpubmed:18660514
imex:IM-26779
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-20620458
imex:IM-26779-9
Confidence scoreintact-miscore:0.52
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f3
comment:As shown in Figure 3, Par-4 co-immunoprecipitated with E2F1 protein in nuclear extracts from the glutamate-treated hBMSCs, indicating the direct interaction between Par-4 and E2F1. By contrast, in nuclear extracts from the hBMSCs without the treatment of glutamate, Par-4 failed to associate with E2F1.
agonist:"\"glutamate(1-) (CHEBI:14321)\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-bone marrow stroma)
taxid:9606(Homo sapiens bone marrow stroma)
Parameters of the interaction-
Creation date2018/07/10
Update date2018/07/10
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot