| Unique identifier for interactor A | intact:EBI-20620429 |
| Unique identifier for interactor B | uniprotkb:Q01094 |
| Alternative identifier for interactor A | - |
| Alternative identifier for interactor B | intact:EBI-448924 uniprotkb:Q13143 uniprotkb:Q92768 ensembl:ENSP00000345571.5 |
| Aliases for A | psi-mi:diablo_human_e2f1-site_dna-probe(display_short) psi-mi:EBI-20620429(display_long) |
| Aliases for B | psi-mi:e2f1_human(display_long) uniprotkb:Retinoblastoma-associated protein 1(gene name synonym) uniprotkb:Retinoblastoma-binding protein 3(gene name synonym) uniprotkb:PBR3(gene name synonym) uniprotkb:E2F1(gene name) psi-mi:E2F1(display_short) uniprotkb:RBBP3(gene name synonym) uniprotkb:pRB-binding protein E2F-1(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0413"(electrophoretic mobility shift assay) |
| First author | Lu et al. (2008) |
| Identifier of the publication | pubmed:18660514 imex:IM-26779 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-20620451 imex:IM-26779-7 |
| Confidence score | intact-miscore:0.52 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Deoxyribonucleic acid |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f4c comment:"\"The neutralizing antibody against E2F1 caused disappearance of both the faster and the slower migrating complex, thus indicating the presence of E2F1 in both the complexes (Figure 4C, lane 5). These results supported that it was E2F1, not Par-4, in Par-4-E2F1 proteins complex that directly bound to Smac promoter, and that Par-4 might indirectly exert its transcriptional control on Smac gene though interacting with E2F1. The BS3 E2F1-binding site was also used as a probe to perform EMSA with nuclear extracts from the hBMSCs without treatment of glutamate. However, no DNA–protein complex was found (Figure 4C, lane 7).\"" agonist:"\"glutamate(1-) (CHEBI:14321)\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2018/07/10 |
| Update date | 2025/03/12 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Molecular weight estimation by autoradiography |
| Participant identification method for interactor B | Molecular weight estimation by autoradiography |