Curation Details
Interaction ID: IM-26779-1

Unique identifier for interactor Aensembl:ENSG00000184047
Unique identifier for interactor Buniprotkb:Q01094
Alternative identifier for interactor Aintact:EBI-20620404
Alternative identifier for interactor Bintact:EBI-448924
ensembl:ENSP00000345571.5
uniprotkb:Q13143
uniprotkb:Q92768
Aliases for Auniprotkb:DIABLO(gene name)
psi-mi:DIABLO(display_short)
uniprotkb:SMAC(gene name synonym)
ensembl:dbloh_human_gene(shortlabel)
psi-mi:ENSG00000184047(display_long)
Aliases for Bpsi-mi:e2f1_human(display_long)
uniprotkb:Retinoblastoma-associated protein 1(gene name synonym)
uniprotkb:Retinoblastoma-binding protein 3(gene name synonym)
uniprotkb:PBR3(gene name synonym)
uniprotkb:E2F1(gene name)
psi-mi:E2F1(display_short)
uniprotkb:RBBP3(gene name synonym)
uniprotkb:pRB-binding protein E2F-1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0402"(chromatin immunoprecipitation assay)
First authorLu et al. (2008)
Identifier of the publicationpubmed:18660514
imex:IM-26779
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-20620398
imex:IM-26779-1
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AGene
Interactor type BProtein
Annotations for the interactionfigure legend:f5
comment:"\"Chromatin immunoprecipitated with anti-Par-4 antibody or anti-E2F1 antibody was subjected to PCR using primers representing BS2 (-542 to -535 bp relative to ATG) site, another previously reported E2F1-binding site. No DNA could be amplified from the chromatins, (data not shown), demonstrating that Par-4 and E2F1 specifically bind to the BS3 (-200 to -193 bp relative to ATG) site on the Smac promoter.\""
agonist:"\"glutamate(1-) (CHEBI:14321)\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-bone marrow stroma)
taxid:9606(Homo sapiens bone marrow stroma)
Parameters of the interaction-
Creation date2018/07/10
Update date2022/07/06
negative Boolean valuefalse
Feature(s) for interactor Asufficient binding region:?-?
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APrimer specific pcr
Participant identification method for interactor BPrimer specific pcr