| Unique identifier for interactor A | uniprotkb:Q07889 |
| Unique identifier for interactor B | uniprotkb:Q9UNS2 |
| Alternative identifier for interactor A | intact:EBI-297487 uniprotkb:A8K2G3 uniprotkb:B4DXG2 ensembl:ENSP00000384675.2 intact:EBI-28968641 |
| Alternative identifier for interactor B | intact:EBI-350590 uniprotkb:B4DY81 uniprotkb:B2R683 ensembl:ENSP00000268717.5 uniprotkb:O43191 uniprotkb:Q7LDR6 |
| Aliases for A | psi-mi:sos1_human(display_long) uniprotkb:SOS1(gene name) psi-mi:SOS1(display_short) |
| Aliases for B | psi-mi:csn3_human(display_long) uniprotkb:COPS3(gene name) psi-mi:COPS3(display_short) uniprotkb:CSN3(gene name synonym) uniprotkb:JAB1-containing signalosome subunit 3(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0006"(anti bait coimmunoprecipitation) |
| First author | Zarich et al. (2019) |
| Identifier of the publication | pubmed:30631038 imex:IM-26693 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-21018382 imex:IM-26693-4 |
| Confidence score | intact-miscore:0.58 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f2d comment:"\"Further confirmatory evidence supporting the in vivo interaction between Sos1 and the COP9 signalosome was obtained in similar, complementary assays using antibodies against CSN3 and Sos1 on lysates of cultured mouse NIH3T3 (not shown) or human HeLa cells (Fig. 2d), as well as of primary MEFs derived from WT or conditional, TAMinducible, Sos1-KO mice (Fig. 2e).\"" full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-hela) taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell) |
| Parameters of the interaction | - |
| Creation date | 2019/01/14 |
| Update date | 2019/01/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |