Unique identifier for interactor A | uniprotkb:Q9UNS2 |
Unique identifier for interactor B | uniprotkb:Q07889 |
Alternative identifier for interactor A | intact:EBI-350590 uniprotkb:B4DY81 uniprotkb:B2R683 ensembl:ENSP00000268717.5 uniprotkb:O43191 uniprotkb:Q7LDR6 |
Alternative identifier for interactor B | intact:EBI-297487 uniprotkb:A8K2G3 uniprotkb:B4DXG2 ensembl:ENSP00000384675.2 intact:EBI-28968641 |
Aliases for A | psi-mi:csn3_human(display_long) uniprotkb:COPS3(gene name) psi-mi:COPS3(display_short) uniprotkb:CSN3(gene name synonym) uniprotkb:JAB1-containing signalosome subunit 3(gene name synonym) |
Aliases for B | psi-mi:sos1_human(display_long) uniprotkb:SOS1(gene name) psi-mi:SOS1(display_short) |
Interaction detection methods | psi-mi:"MI:0096"(pull down) |
First author | Zarich et al. (2019) |
Identifier of the publication | pubmed:30631038 imex:IM-26693 |
NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
Interaction types | psi-mi:"MI:0915"(physical association) |
Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
Interaction identifier(s) in the corresponding source database | intact:EBI-21018359 imex:IM-26693-2 |
Confidence score | intact-miscore:0.58 |
Complex expansion | - |
Biological role A | Unspecified role |
Biological role B | Unspecified role |
Experimental role A | Prey |
Experimental role B | Bait |
Interactor type A | Protein |
Interactor type B | Protein |
Annotations for the interaction | figure legend:fig. 2a comment:"\"Cytoplasmic extracts from HeLa cells were incubated with purified GST-HD, GST-DH-PH, and GST-NDP fusion proteins coupled to glutathione–sepharose beads that were subsequently tested by means of immunoblotting with antibodies against CSN3 (Fig. 2a). Whereas purified GSTDHPH did not bind any CSN3, the GST-HD and GSTNDP peptides bound roughly similar amount of cellular CSN3 in lysates of actively growing HeLa cells (Fig. 2a, upper panel).\"" full coverage:Only protein-protein interactions curation depth:imex curation |
NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
Parameters of the interaction | - |
Creation date | 2019/01/14 |
Update date | 2019/01/14 |
negative Boolean value | false |
Feature(s) for interactor A | - |
Feature(s) for interactor B | glutathione s tranferase tag:?-? necessary binding region:1-640 |
Stoichiometry for interactor A | - |
Stoichiometry for interactor B | - |
Participant identification method for interactor A | Western blot |
Participant identification method for interactor B | Western blot |