Curation Details
Interaction ID: IM-26660-679

Unique identifier for interactor Auniprotkb:Q06124
Unique identifier for interactor Buniprotkb:Q02763
Alternative identifier for interactor Aintact:EBI-297779
uniprotkb:Q96HD7
uniprotkb:A8K1D9
ensembl:ENSP00000340944.3
intact:EBI-14351608
intact:EBI-11988773
intact:EBI-13004965
Alternative identifier for interactor Bintact:EBI-2257090
uniprotkb:A8K6W0
uniprotkb:Q5TCU2
uniprotkb:B4DH20
uniprotkb:B4DHD3
uniprotkb:E7EWI2
uniprotkb:Q8IV34
uniprotkb:D3DRK5
ensembl:ENSP00000369375.4
Aliases for Apsi-mi:ptn11_human(display_long)
uniprotkb:PTPN11(gene name)
psi-mi:PTPN11(display_short)
uniprotkb:PTP2C(gene name synonym)
uniprotkb:SHPTP2(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 2C(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym)
uniprotkb:SH-PTP3(gene name synonym)
uniprotkb:SH-PTP2(gene name synonym)
Aliases for Bpsi-mi:tie2_human(display_long)
uniprotkb:TEK(gene name)
psi-mi:TEK(display_short)
uniprotkb:TIE2(gene name synonym)
uniprotkb:Tyrosine-protein kinase receptor TIE-2(gene name synonym)
uniprotkb:Tyrosine-protein kinase receptor TEK(gene name synonym)
uniprotkb:Tunica interna endothelial cell kinase(gene name synonym)
uniprotkb:p140 TEK(gene name synonym)
uniprotkb:Endothelial tyrosine kinase(gene name synonym)
uniprotkb:Tyrosine kinase with Ig and EGF homology domains-2(gene name synonym)
uniprotkb:VMCM(gene name synonym)
uniprotkb:VMCM1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0112"(ubiquitin reconstruction)
First authorYao et al. (2017)
Identifier of the publicationimex:IM-26660
doi:10.1016/j.molcel.2016.12.004
pubmed:28065597
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-21226162
imex:IM-26660-679
Confidence scoreintact-miscore:0.37
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:sf2b
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:4932(yeasx)
taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
Parameters of the interaction-
Creation date2018/10/16
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Anubg:n-n
mutation increasing interaction:459-459,425-425
mutation with no effect:459-459
Feature(s) for interactor Bcub:c-c
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant