Curation Details
Interaction ID: IM-26660-517

Unique identifier for interactor Auniprotkb:P29350
Unique identifier for interactor Buniprotkb:P04626
Alternative identifier for interactor Aintact:EBI-78260
intact:EBI-28977917
uniprotkb:Q969V8
ensembl:ENSP00000326010.9
uniprotkb:A8K306
uniprotkb:G3V0F8
uniprotkb:Q9UK67
Alternative identifier for interactor Bintact:EBI-641062
uniprotkb:Q14256
uniprotkb:Q6LDV1
uniprotkb:Q9UMK4
uniprotkb:B2RZG3
uniprotkb:B4DHN3
uniprotkb:X5D2V5
ensembl:ENSP00000269571.4
Aliases for Apsi-mi:ptn6_human(display_long)
uniprotkb:PTPN6(gene name)
psi-mi:PTPN6(display_short)
uniprotkb:HCP(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)
uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)
uniprotkb:SH-PTP1(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase SHP-1(gene name synonym)
uniprotkb:PTP1C(gene name synonym)
Aliases for Bpsi-mi:erbb2_human(display_long)
uniprotkb:p185erbB2(gene name synonym)
uniprotkb:MLN19(gene name synonym)
uniprotkb:Proto-oncogene c-ErbB-2(gene name synonym)
uniprotkb:Tyrosine kinase-type cell surface receptor HER2(gene name synonym)
uniprotkb:Proto-oncogene Neu(gene name synonym)
uniprotkb:ERBB2(gene name)
psi-mi:ERBB2(display_short)
uniprotkb:HER2(gene name synonym)
uniprotkb:NEU(gene name synonym)
uniprotkb:NGL(gene name synonym)
uniprotkb:Metastatic lymph node gene 19 protein(gene name synonym)
Interaction detection methodspsi-mi:"MI:0112"(ubiquitin reconstruction)
First authorYao et al. (2017)
Identifier of the publicationimex:IM-26660
doi:10.1016/j.molcel.2016.12.004
pubmed:28065597
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-21202251
imex:IM-26660-517
Confidence scoreintact-miscore:0.37
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F1B SF2B
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:4932(yeasx)
taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
Parameters of the interaction-
Creation date2018/10/16
Update date2024/07/03
negative Boolean valuefalse
Feature(s) for interactor Anubg:n-n
mutation increasing interaction:453-453,419-419
mutation increasing interaction:453-453
Feature(s) for interactor Bmutation with no effect:753-753
cub:c-c
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant