Curation Details
Interaction ID: IM-26660-459

Unique identifier for interactor Auniprotkb:Q06124
Unique identifier for interactor Buniprotkb:P35968
Alternative identifier for interactor Aintact:EBI-297779
uniprotkb:Q96HD7
uniprotkb:A8K1D9
ensembl:ENSP00000340944.3
intact:EBI-14351608
intact:EBI-11988773
intact:EBI-13004965
Alternative identifier for interactor Bintact:EBI-1005487
uniprotkb:O60723
uniprotkb:Q14178
ensembl:ENSP00000263923.4
intact:EBI-28976571
uniprotkb:A2RRS0
uniprotkb:B5A925
uniprotkb:C5IFA0
Aliases for Apsi-mi:ptn11_human(display_long)
uniprotkb:PTPN11(gene name)
psi-mi:PTPN11(display_short)
uniprotkb:PTP2C(gene name synonym)
uniprotkb:SHPTP2(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 2C(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym)
uniprotkb:SH-PTP3(gene name synonym)
uniprotkb:SH-PTP2(gene name synonym)
Aliases for Bpsi-mi:vgfr2_human(display_long)
uniprotkb:Kinase insert domain receptor(gene name synonym)
uniprotkb:Protein-tyrosine kinase receptor flk-1(gene name synonym)
uniprotkb:KDR(gene name)
psi-mi:KDR(display_short)
uniprotkb:FLK1(gene name synonym)
uniprotkb:Fetal liver kinase 1(gene name synonym)
uniprotkb:VEGFR2(gene name synonym)
Interaction detection methodspsi-mi:"MI:0112"(ubiquitin reconstruction)
First authorYao et al. (2017)
Identifier of the publicationimex:IM-26660
doi:10.1016/j.molcel.2016.12.004
pubmed:28065597
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-21227120
imex:IM-26660-459
Confidence scoreintact-miscore:0.37
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:sf2b
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:4932(yeasx)
taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
Parameters of the interaction-
Creation date2018/10/16
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Anubg:n-n
mutation increasing interaction:459-459,425-425
mutation with no effect:459-459
Feature(s) for interactor Bcub:c-c
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant