Curation Details
Interaction ID: IM-26660-229

Unique identifier for interactor Auniprotkb:P29350
Unique identifier for interactor Buniprotkb:P08069
Alternative identifier for interactor Aintact:EBI-78260
intact:EBI-28977917
uniprotkb:Q969V8
ensembl:ENSP00000326010.9
uniprotkb:A8K306
uniprotkb:G3V0F8
uniprotkb:Q9UK67
Alternative identifier for interactor Bintact:EBI-475981
uniprotkb:Q14CV2
uniprotkb:B1B5Y2
uniprotkb:Q9UCC0
ensembl:ENSP00000497069.1
Aliases for Apsi-mi:ptn6_human(display_long)
uniprotkb:PTPN6(gene name)
psi-mi:PTPN6(display_short)
uniprotkb:HCP(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)
uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)
uniprotkb:SH-PTP1(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase SHP-1(gene name synonym)
uniprotkb:PTP1C(gene name synonym)
Aliases for Bpsi-mi:igf1r_human(display_long)
uniprotkb:Insulin-like growth factor I receptor(gene name synonym)
uniprotkb:IGF1R(gene name)
psi-mi:IGF1R(display_short)
Interaction detection methodspsi-mi:"MI:0112"(ubiquitin reconstruction)
First authorYao et al. (2017)
Identifier of the publicationimex:IM-26660
doi:10.1016/j.molcel.2016.12.004
pubmed:28065597
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-20981980
imex:IM-26660-229
Confidence scoreintact-miscore:0.51
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F1B SF2B
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:4932(yeasx)
taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
Parameters of the interaction-
Creation date2018/10/16
Update date2024/07/03
negative Boolean valuefalse
Feature(s) for interactor Anubg:n-n
mutation decreasing interaction:453-453
mutation decreasing interaction:453-453,419-419
Feature(s) for interactor Bcub:c-c
mutation with no effect:1033-1033
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant