Curation Details
Interaction ID: IM-26660-223

Unique identifier for interactor Auniprotkb:P00533
Unique identifier for interactor Buniprotkb:P29353
Alternative identifier for interactor Aintact:EBI-297353
uniprotkb:Q9BZS2
uniprotkb:Q9GZX1
uniprotkb:Q9H2C9
uniprotkb:Q9H3C9
uniprotkb:Q9UMD7
uniprotkb:Q9UMD8
uniprotkb:Q9UMG5
uniprotkb:O00688
uniprotkb:O00732
uniprotkb:P06268
uniprotkb:Q14225
uniprotkb:Q92795
intact:EBI-28985169
uniprotkb:Q68GS5
ensembl:ENSP00000275493.2
Alternative identifier for interactor Bintact:EBI-78835
uniprotkb:O15290
uniprotkb:Q5T180
uniprotkb:Q5T183
uniprotkb:Q5T184
uniprotkb:Q5T185
uniprotkb:Q5T186
uniprotkb:Q8N4K5
uniprotkb:Q96CL1
uniprotkb:B5BU19
uniprotkb:D3DV78
ensembl:ENSP00000357430.5
Aliases for Apsi-mi:egfr_human(display_long)
uniprotkb:ERBB1(gene name synonym)
uniprotkb:EGFR(gene name)
psi-mi:EGFR(display_short)
uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym)
uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym)
uniprotkb:ERBB(gene name synonym)
uniprotkb:HER1(gene name synonym)
Aliases for Bpsi-mi:shc1_human(display_long)
uniprotkb:SHC1(gene name)
psi-mi:SHC1(display_short)
uniprotkb:SHC(gene name synonym)
uniprotkb:SHCA(gene name synonym)
uniprotkb:Src homology 2 domain-containing-transforming protein C1(gene name synonym)
uniprotkb:SHC-transforming protein A(gene name synonym)
uniprotkb:SHC-transforming protein 3(gene name synonym)
Interaction detection methodspsi-mi:"MI:0112"(ubiquitin reconstruction)
First authorYao et al. (2017)
Identifier of the publicationimex:IM-26660
doi:10.1016/j.molcel.2016.12.004
pubmed:28065597
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-20977058
imex:IM-26660-223
Confidence scoreintact-miscore:0.98
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f3b
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293t)
taxid:9606(Homo sapiens HEK293T embryonic kidney cell)
Parameters of the interaction-
Creation date2018/10/16
Update date2024/07/10
negative Boolean valuefalse
Feature(s) for interactor Acub:c-c
Feature(s) for interactor Bnub:n-n
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant